Agitation

Question 1

What is the treatment for MILD agitation in adults?

SAT +1

Answer 1

Olanzapine 10mg Oral

FRAIL = 5mg oral

Repeat once after 20 mins

Question 2

What is the treatment for MODERATE agitation in adults?

SAT +2

Answer 2

5 - 10 mg IM
FRAIL - 2.5-5mg

Repeat 10mins max 20mg

Question 3

What is the treatment for SEVERE agitation in adults?

SAT +3

Answer 3

Ketamine IM
<60kg = 200mg
60-90kg = 300mg
>90kg = 400mg

Question 4

What are the contras for olanzapine

Answer 4

Nil

Question 5

What are contras for ketamine

Answer 5

Suspected nontraumatic brain injury with severe hypertention SBP over 180

Question 6

what are the precautions for olanzapine

Answer 6

1. may be less effective if agitation due to drug intoxication
2. elderly/frail

Question 7

what are the side effects for olanzapine

Answer 7

sedation

dizziness

Question 8

what are the precautions for ketamine

Answer 8

may exacerbate cardiovascular conditions due to effects on HR and BP

Question 9

what are the side effects for keytamine

Answer 9

hypertension
tachycardia
emergence reactions
resp depression and apnoea
nausea and vomiting

Question 10

what is the onset peak and duration for ketamine IM

Answer 10

onset - 3-4mins

duration - 12-25mins

Question 11

what is the onset peak and duration for olanzapine

Answer 11

onset - 15mins

duration - 12-24 hours