Thyroid physiology Flashcards

1
Q

which hormone is released at hypothalamus?

A

thyroid releasing hormone

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2
Q

which hormone is released at ant. pituitary?

A

thyroid stimulating hormone

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3
Q

what connect hypothalamus to ant. pituitary?

nerves or blood

A

blood

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4
Q

thyroid stimulating hormone goes to what organ?

A

thyroid gland

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5
Q

thyroid stimulating hormone stimulated what transporter at the thyroid gland?

A

NaI transporter

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6
Q

NaI transporter function?

A

take iodine into thryoid

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7
Q

thyroid precursor is called what?

A

thyroglobulin

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8
Q

what process converts thyroglobulin into thyroid hormone?

A

iodination

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9
Q

what must you add to thyroglobulin to turn into thyroid hormones?

A

iodine

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10
Q

tumour marker for thyroid gland?

A

thyroglobulin

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11
Q

full names of two main thyroid hormones?

A

thyroxine

triiodothyronine

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12
Q

short names of the two main thyroid hormones?

A

t4

t3

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13
Q

which thyroid hormone is most common in blood?

A

t4 - thyroxine

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14
Q

t3 is aka?

A

triiodothyronine

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15
Q

which thyroid hormone has longer half life?

A

t4 - thyroxine

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16
Q

which thyroid hormone has is more active?

A

t3 - triiodothyronine

17
Q

which thyroid hormone has one less iodine?

A

t3 - triiodothyronine

18
Q

which thyroid hormone gives more -ve feedback?

A

t4 - thyroxine

19
Q

thyroid hormones travel through to blood to target cells,

which thyroid hormones converts into which?

A

t4 converts to t3

20
Q

normal thyroid levels is called what?

A

Euthyroidism

21
Q

which chemical can inhibit the NaI transporter?

A

perchlorate

22
Q

% of t4 compared to t3 in blood

A

t4 - 90%

t3 - 10%

23
Q

functions of thyroid hormones (t4 and t3)

-4

A
  • Regulates energy
  • Metabolism
  • Drives SNS
  • ↑O2 consumption
24
Q

examples of primary problems of the thyroid gland?

-4 main ones

A

graves
goitre’s
hashimoto’s
riedal

25
Q

most common hyperthyroid cause?

A

grave’s

26
Q

most common hypothyroid cause?

A

hashimoto’s