DIURETICS

Question 1

carbonic anhydrase inhibitors

Answer 1

acetazolamide

Question 2

loop diuretics

Answer 2

furosemide, ethacrynic acid

Question 3

thiazide diuretics

Answer 3

hydrochlorothiazide, chlorthalidone, metolazone

Question 4

K sparing diuretics

Answer 4

spironolactone

Question 5

osmotic diuretics

Answer 5

mannitol

Question 6

proximal convoluted tubule

Answer 6

acetazolamide:
not a great diuretic
metabolic acidosis
contra w/ liver failure

Question 7

acending loop

Answer 7

furosemide, ethacrynic acid:
most effective diuretics
ototoxicity, uric acid build up (gout)
Ca is SECRETED (pee'd out)
w/ NSAID diuretic effects decreased

Question 8

distal convoluted tubule

Answer 8

hydrochlorothiazide, chlorthalidone, metolazone (thiazides):
inhibits active transport of Na out of tubule
no effect on acid base
Ca is RETAINED in syst

Question 9

collecting duct

Answer 9

spironolactone (K sparing drugs):
inhibit Na reabsorption (Na pee’d out, K kept in syst)
inhibit K secretion
inhibits aldosterone
see gynacomastia/menstrual irregularities

Question 10

manitol

Answer 10

osmotic drug used in head trauma to reduce ICP and in patients with renal failure