PAIN MANAGEMENT Flashcards
neuropathic pain
“nerve pain”-chronic pain that occurs when nerves in CNS become injured
nociceptive pain
stimulation of pain receptors (tissue inflammation, injury etc)
idiopathic pain
no apparent underlying cause
psychogenic pain
pain thought to be due to psych problems
peripheral agents
acetaminophen (tylenol), NSAIDs (ibuprophen, naproxen)
acetaminophen
inhibits prostaglandin synthesis in CNS, used for pain, very low anti inflamm, pain reliever (analgesic) and fever reducer (antipyretic)
ibuprophen, naproxen
reversibly inhibiting cyclooxygenase enzymes (which inhibit synthesis of prostaglandins); anti inflammatory, antipyretic and analgesic
opiods
bind to receptors in CNS to mimic endorphins, when bound to signaling neuron it lessens amount of chemical messengers;
bisphosphates
used for bone remodeling osteoporosis, bone metastases, hypercalcemia; decrease the formation of osteoclasts (delay or prevent bone metastases that cause pain)
neuropathic agents
anti depressants, anticonvulsants, local anesthetics
antidepressants
thought to inhibit reuptake of norepi and serotonin in the spinal cord (both influence descending pain pathways)
anticonvulsants
decrease neuronal hyperexcitability (fundamental to seizures and neuropathic type pain)