VASODILATORS

Question 1

Ca channel blockers

Answer 1

dihydropyridines
phenylalkylamines
benzothiazepines
(only dilate arterioles, not veins)

Question 2

ACE inhibitors

Answer 2

lisinopril, captopril

Question 3

angiotensin receptor blockers

Answer 3

valsartan, losartan

Question 4

direct vasodilators

Answer 4

hydralazine, nitroglycerine, isosorbide dinitrate

Question 5

phosphodiesterase inhibitors

Answer 5

sildenafil (viagra), tadalafil (cialis)

Question 6

dihydropyridines

Answer 6

Ca channel blocker:
nifedipine, amlodipine
much more selective for Ca channels in vascular

Question 7

phenylalkylamines

Answer 7

Ca channel blocker:
verapamil
significant effects on both heart and vasculature

Question 8

benzothiazepines

Answer 8

Ca channel blocker:
diltiazem
affects both cardiac and vasculature

Question 9

lisinopril, captopril

Answer 9

ACE inhibitors:
decrease angiotensin II (thereby decreasing aldosterone), increase bradykinin (NO)
vasodilate BOTH areterioles and veins

Question 10

valsartan, losartan

Answer 10

ARB’s
very similar action of ACE inhibitors
no bradykinin action
no pregnant pts