11. Transfusion Therapy in Selected Patients Flashcards
(19 cards)
What type of patient would require..
- irradiated products (avoid GVHD)
- mostly PLTs, but also RBC, plasma
- PLTs usually apheresis
Oncology
Removal of abnormal cells, plasma, plasma constituents
Therapeutic apheresis
2 possible toxic symptoms due to massive transfusion
- hypocalcemia
- citrate toxicity
What type of patient would require..
- leukoreduced RBCs
- recombinant EPO
Chronic renal disease
What type of patient would require..
-therapeutic plasma exchange
TTP and ITP
What type of patient would require..
- factor derivatives for factor that is lacking
- sometimes PLTs
- fibrinogen
- cryoprecipitate
Hemostatic disorders
What type of patient would require..
- avoid transfusion if possible
- least incompatible transfusion
Immune hemolytic anemia
Replacement of one or more blood volumes in a 24 hr period
Massive transfusion
Autoantibody against platelets
ITP
Decreased survival of RBCs due to antibody coating the RBC membrane
Immune hemolytic anemia
During cardiac surgery, patients are mainly transfused with this product
Platelets
Heparin increases ____
PTT
Caused by a deficiency or antibody to protease that cleaves vWF
TTP
During an urgent transfusion (emergency), this type of blood may be given to females of child bearing age
Rh neg, K neg
During cardiac surgery, hypothermia is usually a sign of..?
Low PLTs
What type of patient would require..
-therapeutic cytapheresis
Sickle cell anemia
During cardiac surgery, heparin excess is corrected with..?
Protamine sulfate
During an urgent transfusion (emergency), a lot of this product is transfused
volume expanders: crystalloids (like saline), colloids (albumin)
Red cells contain abnormal hemoglobin chains and are destroyed by spleen or in bone marrow
Thalassemia
