7. Blood Donor Testing Flashcards Preview

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Flashcards in 7. Blood Donor Testing Deck (31):
1

PLTs are stored at ___ for up to __ days

RT; 7 days

2

HTLV confirmatory test?

HTLV Western blot

3

PLTs are stored at room temp up to how long?

7 days

4

a common community acquired infection that lies dormant in white blood cells and is harmless for most of the population

Cytomegalovirus (CMV)

5

What is a "window period"

Period between the time a donor becomes infected and when it can be detected

6

Phenotyping for these for 6 are routinely performed on a subset of repeat donor sample

C/c E/e Kell Duffy Kidd S/s

7

3 things that happen during a lookback investigation?

- Donor deferred; their previous donations are investigated

- Hospitals that received blood are notified and asked to ID recipients

- Recipients are tested

8

What test is performed on first time donor that looks Rh NEG

Weak D test

9

Environment where syphilis can't survive

72 hrs in citrated blood at 1-6 degC

72 hrs at RT

10

The process of identifying and contacting recipients of blood components from a donor who, on a subsequent donation or testing, is confirmed to have tested positive for the presence of an infectious agent

LOOK BACK

11

This is the process of investigating a report of transfusion-associated infection in blood recipients who have already received blood components.

TRACEBACK

12

The only component capable of transmitting syphilis infection

Platelets

13

Purpose of TRACEBACK investigation?

Determine if any donor who provided blood for that recipient has tested positive for an infectious agent

14

_____ has been associated with adult T-cell leukemia
and myelopathy / tropical spastic paraparesis (HAM/TSP)

HTLV-I

15

Why is the risk of CMV infection related to blood products low in Canada

CMV = cell-associated virus and cellular components get LEUKOREDUCED in Canada

16

How often can plateletpheresis be done?

Every 2 weeks (14 days)

17

Minimum weight requirement to donate?

50kg 110lbs

18

Disease caused by Treponema pallidum

Syphilis

19

How does MHA-TP work

Sheep RBC coated w/ T. pallidum antigen => test for agglutination w/ patient plasma

20

How often can plasmapheresis be done?

Every week (7 days)

21

When would chagas be tested?

Donor is "at-risk" as indicated by questionnaire

22

Why are platelets the only component capable of transmitting syphilis?

Storage @RT (cannot survive cold)

23

minimum Hgb male and female

Female 125 g/L
Male 130 g/L

24

Assay used to detect antibody to T. cruzi

Chemiluminescent

25

________ transfusions require CMV negative products

Intrauterine

26

How often can male donors donate whole blood? Female?

Male - 56 days
Females - 84 days

27

Test for Treponema pallidum

MHA-TP micro hemagglutination test

28

How are platelet units tested for bacterial contamination?

Automated blood culture system

29

Organism that causes chagas

Trypanosoma cruzi

30

Most ppl w/ _______ are asymptomatic or have mild mono-like symptoms

CMV

31

3 steps in donor screening

1. Registration
2. Health history review
3. Physical exam