Flashcards in 7. Blood Donor Testing Deck (31):
PLTs are stored at ___ for up to __ days
RT; 7 days
HTLV confirmatory test?
HTLV Western blot
PLTs are stored at room temp up to how long?
a common community acquired infection that lies dormant in white blood cells and is harmless for most of the population
What is a "window period"
Period between the time a donor becomes infected and when it can be detected
Phenotyping for these for 6 are routinely performed on a subset of repeat donor sample
C/c E/e Kell Duffy Kidd S/s
3 things that happen during a lookback investigation?
- Donor deferred; their previous donations are investigated
- Hospitals that received blood are notified and asked to ID recipients
- Recipients are tested
What test is performed on first time donor that looks Rh NEG
Weak D test
Environment where syphilis can't survive
72 hrs in citrated blood at 1-6 degC
72 hrs at RT
The process of identifying and contacting recipients of blood components from a donor who, on a subsequent donation or testing, is confirmed to have tested positive for the presence of an infectious agent
This is the process of investigating a report of transfusion-associated infection in blood recipients who have already received blood components.
The only component capable of transmitting syphilis infection
Purpose of TRACEBACK investigation?
Determine if any donor who provided blood for that recipient has tested positive for an infectious agent
_____ has been associated with adult T-cell leukemia
and myelopathy / tropical spastic paraparesis (HAM/TSP)
Why is the risk of CMV infection related to blood products low in Canada
CMV = cell-associated virus and cellular components get LEUKOREDUCED in Canada
How often can plateletpheresis be done?
Every 2 weeks (14 days)
Minimum weight requirement to donate?
Disease caused by Treponema pallidum
How does MHA-TP work
Sheep RBC coated w/ T. pallidum antigen => test for agglutination w/ patient plasma
How often can plasmapheresis be done?
Every week (7 days)
When would chagas be tested?
Donor is "at-risk" as indicated by questionnaire
Why are platelets the only component capable of transmitting syphilis?
Storage @RT (cannot survive cold)
minimum Hgb male and female
Female 125 g/L
Male 130 g/L
Assay used to detect antibody to T. cruzi
________ transfusions require CMV negative products
How often can male donors donate whole blood? Female?
Male - 56 days
Females - 84 days
Test for Treponema pallidum
MHA-TP micro hemagglutination test
How are platelet units tested for bacterial contamination?
Automated blood culture system
Organism that causes chagas
Most ppl w/ _______ are asymptomatic or have mild mono-like symptoms