Exam 5: Kays TB Flashcards
is latent TB infectious
NO
Standard therapy for TB
RIPE
Regimen 1 Intensive phase options for TB
Rifampin, INH, pyrazinamide, and ethambutol 7 days/week for 56 doses (8 weeks)
OR
5 days/week for 40 doses
Regimen 1 continuation phase: preferred
INH and rifampin 7 days/week for 126 doses (18 weeks) OR 5 days/week for 90 doses (18)
Regimen 1 continuation phase: alternative
INH and rifampin 3 times weekly for 54 doses (18 weeks)
regimen 2 intensive phase
INH, rifampin, pyrazinamide, and ethambutol three times weekly for 24 doses (8 weeks)
regimen 2 continuation phase
inh and rifampin 3 times weekly for 54 doses (18 weeks)
regimen 3 intensive phase
INH, rifampin, pyrazinamide, and ethambutol 7 days/week for 14 doses (2 weeks), then twice weekly for 12 doses (6 weeks)
regimen 3 continuation phase
INH and rifampin twice weekly for 36 doses (18 weeks)
Do not use _______ in HIV-infected patients or patients with smear-positive and/or cavitary disease
twice-weekly regimens
Administer ______ to patients receiving INH
pyridoxine (vit B6)
ART and TB therapy
2 weeks: CD4 <50
8-12 weeks: CD4 >50
Rifampin and dolutegravir relationship
dolutegravir may be administered BID rather than daily
FQ DOC in intensive stage
moxifloxacin
Treatment options of latent TB
- rifampin 600mg x4 month
- INH 900 + rifapentine 900 x12 w
- INH + rifampin x3 m
