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402: Rheum and derm > Inflammatory skin conditions > Flashcards

Inflammatory skin conditions Flashcards

1
Q

First line management for polymorphic light eruption

A

Oral antihistamines
- Loratidine

Hydrocortisone

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2
Q

Eczema rash is characterised by…

A

Vesicles/ papules on a erythematous base

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3
Q

Complications of eczema

A

Eczema herpeticum

Molluscum contagiosum

Secondary bacterial infections

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4
Q

What % of children are affected with eczema?

A

20%

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5
Q

Eczema is associated with…

A

Positive family history

Atopic history: asthma, allergic rhinitis

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6
Q

General advise for atopic dermatitis

A

Avoid fragranced creams/ soaps

Avoid foaming agents (SLS)/ soaps

Good hydration

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7
Q

First line management for atopic dermatitis

A

Emollient + mild topical steroid (hydrocortisone)

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8
Q

What treatment is indicated for severe atopic dermatitis/ high risk sites

A

Calcineurin inhibitors

- Tacrolimus, pimecrolimus

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9
Q

Calcineurin inhibitors is not licensed in …

A

Age <2

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10
Q

Pompholyx dermatitis typically affects what region?

A

Hands, fingers, soles of feet

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11
Q

Asteatosis is also known as…

A

Eczema craquele

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12
Q

Contact dermatitis involves what hypersensitivity reaction?

A

Type 4

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13
Q

Atopic dermatitis typically affects what regions?

A

Flexors
- inner elbow, back of knees

Extensors in infants

Face

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14
Q

Acute atopic dermatitis can present as…

A

Exudative, vesicular rash

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15
Q

Exacerbating features of atopic dermatitis [4]

A

Allergen exposure

Sweating/ Heat

Severe stress

Hormonal changes in women

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16
Q

Discoid dermatitis presents as…

A

Discoid shaped plaques

- Afffects the limbs

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17
Q

Varicose dermatitis can present as….

A

Erythematous, dry itchy skin

Haemosiderin deposits

Lipodermatosclerosis

Atophie blanche

Corona phlebactatica

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18
Q

Eczema craquele presents as…

A

Dry, cracked skin

Diamond shaped plates in skin
- Separated by red bands

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19
Q

Lichenification describes…

A

Skin thickening as a result of chronic scratching

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20
Q

First line investigation for contact dermatitis

A

Patch test

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21
Q

What scoring system is used for eczema in children?

A

Children’s dermatology life quality index (CDQLI)

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22
Q

What scoring system is used for eczema in adults

A

What scoring system is used for eczema in Adults

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23
Q

General advise for contact dermatitis

A

Avoid the precipitating cause

Avoid soap

Dry skin carefully

Use gloves in hand dermatitis

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24
Q

First line management of contact dermatitis

A

Avoiding/ removing the cause

Potent corticosteroids
- Betnovate/ Dermovate

Emollient

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25
Q

First line management of seborrhoeic dermatitis

A

Non soap cleanser

Topical antifungal (OD 2-4 weeka)
- Ketoconazole/ clotimazole

Mild topical corticosteroid (BD, 1-2 weeks and wean)
- Hydrocortisone

26
Q

Triggers of psoriasis [5]

A

Streptococcal infections (and other infections)

Stress

Medications

Smoking/ alcohol

Skin injury

27
Q

Types of psoriasis

A

Plaque

Pustular

Guttate

Flexural

Erythrodermic (medical emergency)

28
Q

Pustural psoriasis mainly affects what regions?

A

Hands and feet (if localised)

29
Q

Primary care management of psoriasis

A

Emollient

Medium-high potent topical steroids

Salicylic acid

Vitamin D cream (Calcipotriol)

30
Q

______ is a vitamin D cream that can be used to treat psoriasis

A

Calcipotriol

31
Q

Biologics is indicated in psoriasis when…

A

Systemic DMARDs fail/

Body surface areas >10 is affected

32
Q

Lichen planus affecting the mouth carries a risk of…

A

Squamous cell carcinoma

33
Q

Lichen planus is associated with which GI conditions

A

Primary biliary cirrhosis

Hepatitis B/C

34
Q

Wilkham straie describes ________ and is a feature of _______

A

Describes white streaks seen in lichen planus

35
Q

Lichen planus typically affects

A

Flexor surfaces:

Wrist

Forearms

Legs

36
Q

First investigation for lichen planus is ______ which shows ______

A

Skin biopsy and histology

Saw-tooth epidermal hyperplasia

37
Q

Lichen planus typically …

A

Resolves within a year

38
Q

Lichen planus presents as…

A

Skin

  • Pruritic, pupuric/ hyperpigmented patch
  • Polygonal shape
  • Wilkham straie

Nails
- Thin plate, longitudinal ridging

Oral
- White-lacy pattern in buccal mucosa

39
Q

Pharmacological treatment of lichen planus

A

Moderate/ potent steroid
- Betnovate/ Eumovate

Antihistamines for pruritis

40
Q

Pharmacological treatment of lichen planus

A

Moderate/ potent steroid
- Betnovate/ Eumovate

Antihistamines for pruritis

41
Q

What drugs can trigger lichen planus?

A

Gold

Quinine

Thiazide

42
Q

Examples of medications that exacerbate psoriasis

A

Cardiac drugs

  • Beta blockers
  • ACEi

Antimalarials

Lithium

NSAIDs

43
Q

First line management for mild acne

A

Topical benzoyl peroxide / topical retinoids

44
Q

First line management for moderate acne

A 
Topical macrolide (clindamycin) + topical benzoyl peroxide/ retinoid
- Antibiotics used up to 6 weeks
45
Q

Second line management for moderate acne

A

Oral antibiotic (lymecycline) + topical retinoids/ benzoyl peroxide/ COCP

46
Q

Management of severe, cystic acne

A

Oral isotretinoin

47
Q

Side effects of retinoids

A

Dry skin

Low mood

Hypersensitivity to the sun

48
Q

What COCP is prescribed for acne?

A

Co-cyprindiol (Ethinylestradiol/cyproterone acetate)

49
Q

First line management of urticaria

A

Non-sedating antihistamine

- i.e. cetirizine

50
Q

Examples of drugs that cause urticaria

A

Aspirin/ NSAIDs

Penicillins

Opioids

51
Q

Management of recurrent/ severe urticaria

A

Oral prednisolone

52
Q

Types of urticaria

A

Acute
- IgE, allergy mediated

Chronic

  • Chronic idiopathic
  • Chronic inducible
  • Autoimmune
53
Q

Triggers for chronic, inducible urticaria

A

Exercise

Temperature changes

Pressure

Sunlight

Strong emotions

54
Q

Anti-leukotrienes such as ______ may be used by specialist to manage chronic urticaria

A

Montelukast

55
Q

Erythema nodosum is associated with which chronic diseases?

A

Sarcoidosis

Inflammatory bowel disease

Lymphoma, leukaemia

56
Q

What medications can trigger erythema nodosum

A

COCP

NSAIDs

57
Q

Erythema nodosum describes…

A

Inflammation of subcutaneous fat (panniculitis) on the shin

58
Q

What triggers are associated with erythema nodosum?

A

Infections

  • Strep throat
  • Mycoplasma pnuemoniae
  • TB
  • gastroenteritis

Pregnancy

59
Q

Features of eyrthema multiforme

A

Erythematous, pruritis rash
- Targe lesion

Sides on arm/ legs- spreads to trunk

60
Q

Most common cause of erythema multiforme is…

A

HSV infection

402: Rheum and derm (12 decks)

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