Frontal lobes Flashcards

1
Q

According to Luria, why due frontal lobe patients have difficulty with problem solving?

A

The can access fragmentary operations but cannot combine them into an overall schema

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1
Q

How do lesions to the prefrontal areas affect attention?

A

Tilt emphasis away from internal mental processes toward stimulus-bound behavior

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1
Q

Orbitofrontal circuit

A

Mediation of emotional & social responses

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2
Q

Lesions to the frontal eye fields result in

A

Impaired exploratory eye movements even when spot eye movements are intact

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3
Q

Witzelsucht

A

Tendency to joke inappropriately

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4
Q

Lesions to the motor association areas anterior to M1 lead to

A

Complex deficits of mvmt in absence of weakness, dystonia, dysmetria, or hyperreflexia; reflect a disconnection between cognition & action

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4
Q

Stuss & Benson divided the functions of the frontal lobes into what 2 groups?

A

1st concerned with sequencing behaviors, forming mental sets, & integrating various behaviors 2nd concerned with more primitive processes such as drive, motivation, will

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5
Q

The frontal eye fields project to

A

Superior colliculus, caudate nucleus, PPRF

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6
Q

Mesulam describes 2 general types of frontal lobe syndromes. What are they?

A

Frontal abulia (lesions to heteromodal cortex) Frontal disinhibition (lesions to paralimbic cortex)

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7
Q

Manifestations of frontal lobe syndromes can result from

A

Lesions in the head of the caudate or MD of thalamus, multifocal WM disease, metabolic encephalopathy, multifocal parietal lesions

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8
Q

Personality changes is the hallmark of dysfunction in what frontal lobe circuit?

A

Orbitofrontal

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9
Q

Role of Broca’s speech area

A

Translating neural word forms into articulatory sequence, sequencing words/endings into utterances that have meaning (appropriate syntactic structure)

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10
Q

Dorsolateral prefrontal syndrome

A

Poor problem solving, poor organizational strategies, impaired set-shifting, perseveration, impersistence, memory may be disrupted, apathy & psychomotor slowing, poor motivation/abulia, decreased emotional range

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12
Q

Frontal release signs

A

Reflexes (e.g., grasp, snout, glabellar) that are usually inhibited by the frontal lobes

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13
Q

Fuster’s temporal processing model

A

Prefrontal cortex is principally involved with representing the ‘temporal structure of behavior’; to encode temporal aspects of behaviors, the prefrontal cortex must be involved in the formation of ‘cross-temporal contingencies’

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14
Q

Anterior cingulate circuit

A

Response monitoring, error detection, conflict resolution, inhibition, selective & divided attention, motivation

15
Q

What are the two groups of processes in working memory, according to Mesulam?

A

1) Volitional manipulation (prefrontal dorsolateral) 2) On-line maintenance (both prefrontal & post parietal)

16
Q

According to Norman & Shallice’s framework, what are the 2 basic control mechanisms that determine how we monitor our activities?

A

Automatic contention scheduler (ACS) - automatic & direct priming of stored knowledge by stimuli in the environment or conceptual thought Supervisory attention system (SAS) - conscious awareness of what we know that set the priorities for action (SAS can override ACS); this system is damaged in frontal lobe dysfunction

18
Q

Orbitofrontal syndrome

A

Disinhibited, poor impulse control, distractible, emotional lability/emotional dysregulation

19
Q

Bilateral lesions to which frontal-subcortical circuit can lead to akinetic mutism?

A

Anterior cingulate

21
Q

Medial frontal syndrome

A

Akinetic & apathetic, little initiation of mvmt or speech, lack of interest & indifference, emotional blunting, memory can be impaired, incontinence

22
Q

Utilization behavior

A

Patient uses objects without a specific goal or need (e.g., sipping from an empty cup when satisfied)

23
Q

Dorsolateral circuit

A

Attentional control, working memory, preparatory motor set, response monitoring