inflammation 4 Flashcards
3 outcomes of acute inflammation
complete resolution
healing by connective tissue replacement (fibrosis)
progression to chronic inflammation
complete resolution
restoration of the site of inflammation to normal
outcome if injury short-lived or little tissue destruction occurs
healing by connective tissue replacement (fibrosis)
substantial tissue destruction
tissue cant regenerate
abundant fibrin exudation that cant be cleared
progression to chronic inflammation
if there is persistence of the injurious agent or interference with normal healing
patterns of acute inflammation
serous inflammation
fibrinous inflammation
suppurative inflammation
ulcers
serous inflammation
thin watery fluid derived from plasma or mesothelial cells
mesothelial cells line the peritoneum, pleura and pericardium
fluid in these 3 cavities is called effusion
fibrinous inflammartion
characterized by accumulation of fibrin
fibrinogen (Soluble plasma protein) leaves blood vessel and is converted to fibrin
large vascular leaks or procoagulant stimulus
characteristic of inflammation in body cavity lining
if fibrin not removed, can stimulate proliferation of fibroblasts and vessels and lead to scarring (fibrosis)
suppurative/purulent inflammation
characterized by production of pus/purulent exudate
neutrophils, liquefactive necrosis, edema
pyogenic bacteria (Staph) produce pus
abscess: localized collection of purulent inflammation
ulcers
local defect or excavation of the surface of organ or tissue
mucosa of GI tract
genitourinary tract
skin/subcutis
ulcer
below basement membrane
erosion
superficial
fibrin
insolube protein when fibrinigen crosslinks
acute inflammation
fibrous
collagen
chronic inflammation
