1296 - 1315 Flashcards

1
Q

In the picture you can see the synthesis of both prostacyclins and thromboxanes. Identify the localization of prostacyclin synthesis.

Select one:
a. Platelets
b. Blood vessel walls
c. Red blood cells

A

b. Blood vessel walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

In the picture you can see the synthesis of both prostacyclins and thromboxanes. Identify the localization of thromboxane synthesis.

a. Platelets
b. Blood vessel walls
c. Red blood cells
d. Leukocytes

A

a. Platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What substrate (S) is used by Cyclooxygenase enzyme in the following reaction?

A

a. Arachidonic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Identify the enzyme (E) that catalyses the conversion of Arachidonate to PGG2.

Select one:
a. Cyclooxygenase
b. Peroxidase
c. Lipoxygenase
d. Dehydrogenase

A

a. Cyclooxygenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What product (P) is formed by Thromboxane synthase enzyme in the reaction below?

Select one:
a. TXA2
b. TXB2
c. TXC2
d. TXD2

A

a. TXA2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What product (P) is formed in the last step of thromboxane synthesis?

Select one:
a. TXA2
b. TXB2
c. TXC2
d. TXD2

A

b. TXB2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which enzyme (X) fits in the figure?

Select one:
a. Thromboxane synthase
b. Dehydrogenase
c. Reductase
d. Epimerase

A

a. Thromboxane synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which enzyme (E) fits in the figure?

Select one:
a. Prostacyclin synthase
b. Lipoxigenase
c. Dehydrogenase

A

a. Prostacyclin synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which drug can be used to inhibit the Cyclooxygenase enzyme?

Select one:
a. Aspirin
b. Acyclovir
c. Ezetimibe
d. Lovastatin

A

a. Aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which drug can be used to inhibit the Thromboxane synthase?

A

Imidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

In the picture you can see a synthetic pathway.
Identify the molecules synthetized by this pathway.

a. Leukotrienes
b. Lipoxins
c. Prostaglandins
d. Thromboxanes

A

a. Leukotrienes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

In the picture you can see a synthetic pathway. Identify the molecules synthetized by this pathway.

a. Leukotrienes
b. Lipoxins
c. Prostaglandins
d. Thromboxanes

A

b. Lipoxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. What is the starting material of this synthetic pathway?

Select one:
a. Arachidonic acid
b. Lignoceric acid
c. Behenic acid
d. Stearic acid

A

a. Arachidonic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Which cell type does the leukotriene synthesis occur in?

a. Red blood cells
b. Leukocytes
c. Endothelial cells

A

b. Leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Which cell type does the lipoxin synthesis occur in?

a. Red blood cells
b. Leukocytes
c. Endothelial cells

A

Leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the first synthetized leukotriene (A).

Select one:
a. Leukotriene A4
b. Leukotriene C4
c. Leukotriene D4
d. Leukotriene E4

A

a. Leukotriene A4

17
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the leukotriene marked with A.

Select one:
a. Leukotriene B4
b. Leukotriene C4
c. Leukotriene D4
d. Leukotriene E4

A

a. Leukotriene B4

18
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the leukotriene marked with D

Select one:
a. Leukotriene B4
b. Leukotriene C4
c. Leukotriene D4
d. Leukotriene E4

A

d. Leukotriene E4

19
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the leukotriene marked with B

Select one:
a. Leukotriene B4
b. Leukotriene C4
c. Leukotriene D4
d. Leukotriene E4

A

b. Leukotriene C4

20
Q

In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the leukotriene marked with C

Select one:
a. Leukotriene B4
b. Leukotriene C4
c. Leukotriene D4
d. Leukotriene E4

A

c. Leukotriene D4

21
Q

1315 In the picture you can see the synthesis of leukotrienes and lipoxins. Identify the molecule marked with A.

Select one:
a. Leukotriene B4
b. Leukotriene C4
c. Leukotriene D4
d. Lipoxin

A

d. Lipoxin