1100 - 1295 (1st sem) Flashcards

1
Q

Name the enzyme on the figure

A

A: Acyl-CoA synthetase
B: Carnitine palmitoyltransferase I
C: Carnitine palmitoyltransferase II
D: Carnitine acylcarnitine translocase

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2
Q

Name the cellular compartment/organelle (A - E)

A

A: Cytosol
B: Outer mitoch. Membr.
C: Intermembr. space
D: Inner mitoch. Membr.
E: Mitochondrial matrix

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3
Q

The scheme shows one successful step of the β-oxidation of Palmitoyl-CoA. What is the name of the product labeled with A/B?

A

A: Acyl-CoA
B: Acetyl-CoA

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4
Q

The scheme shows the β-oxidation of fatty acids.
-> What is the name of the enzyme labeled with A?

A

A: Acyl-CoA synthetase

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5
Q

The scheme shows the β-oxidation of fatty acids.
-> What is the name of the enzyme labeled with B?

A

B: Acyl-CoA dehydrogenase

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6
Q

The scheme shows the β-oxidation of fatty acids.
-> What is the name of the enzyme labeled with C?

A

C: Δ2-Enoyl-CoA hydratase

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7
Q

The scheme shows the β-oxidation of fatty acids.
-> What is the name of the enzyme labeled with D?

A

D: L(+)-3-hydroxyacyl-CoA dehydrogenase

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8
Q

The scheme shows the β-oxidation of fatty acids.
-> What is the name of the enzyme labeled with E?

A

E: Thiolase

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9
Q

Name the displayed intermedier in the oxidation process of Linoleic acid.

A

Linoleyl-CoA

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10
Q

Name the displayed intermedier in the oxidation process of Linoleic acid

A

∆3-cis-∆6-cis-Dienoyl-CoA

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11
Q

Name the displayed intermedier in the oxidation process of Linoleic acid

A

∆2-trans-∆6-cis-Dienoyl-CoA

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12
Q

Name the displayed intermedier in the oxidation process of Linoleic acid

A

∆2-trans-∆4-cis-Dienoyl-CoA

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13
Q

Name the displayed intermedier in the oxidation process of Linoleic acid

A

∆3-trans-Enoyl-CoA

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14
Q

Name the displayed intermedier in the oxidation process of Linoleic acid.

A

∆2-trans-Enoyl-CoA

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15
Q

Name the type of the enzyme that catalyzes the shown reaction, part of the oxidation process of Linoleic acid.

A

Isomerase

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16
Q

Name the type of the enzyme that catalyzes the shown reaction, part of the oxidation process of Linoleic acid

A

Isomerase

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17
Q

Name the type of the enzyme that catalyzes the shown reaction, part of the oxidation process of Linoleic acid.

A

Reductase

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18
Q

Name the ketone body labeled with A/B/C.

A

A: Acetoacetate
B: Acetone
C: D(–)-3-Hydroxybutyrate

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19
Q

Which of the two reactions is/are catalyzed by a mitochondrial enzyme?

A

B

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20
Q

Which of the two reactions is/are spontaneous?

A

A

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21
Q

Name enzyme A/B/C/D/E in the chain of ketogenesis.

A

A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase

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22
Q

Name enzyme A in the chain of ketogenesis.

A

A: Acyl-CoA synthetase

(A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase)

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23
Q

Name enzyme B in the chain of ketogenesis.

A

B: Thiolase

(A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase)

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24
Q

Name enzyme C in the chain of ketogenesis.

A

C: HMG-CoA synthase

(A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase)

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25
Q

Name enzyme D in the chain of ketogenesis.

A

D: HMG-CoA lyase

(A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase)

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26
Q

Name enzyme E in the chain of ketogenesis.

A

E: D(–)-3-Hydroxybutyrate dehydrogenase

(A: Acyl-CoA synthetase
B: Thiolase
C: HMG-CoA synthase
D: HMG-CoA lyase
E: D(–)-3-Hydroxybutyrate dehydrogenase)

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27
Q

Name molecule A/B/C/D/E in the chain of ketogenesis.

A

A: Acetoacetyl-CoA
B: Acetyl-CoA
C: 3-Hydroxy-3-methylglutaryl- CoA (Hmg-CoA)
D: Acetoacetate
E: D(–)-3-Hydroxybutyrate

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28
Q

Name enzyme A/B on the figure

A

A: CoA Transferase
B: Thiolase

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29
Q

Name molecule A/B/C/D on the figure.

A

A: Acyl-CoA
B: HMG-CoA
C: 3-Hydroxybutyrate
D: Acetoacetyl-CoA

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30
Q

Name molecule A/B/C on the figure.

A

A: Acetyl-CoA
B: Acetoacetate
C: Acetoacetyl-CoA

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31
Q

Name enzyme A/B on the figure.

A

A: Acetyl-CoA carboxylase
B: Carnitine palmitoyltransferase-I

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32
Q

Name molecule A/B/C on the figure.

A

A: Glucose
B: FFA
C: VLDL

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33
Q

Name molecule A/B/C/D on the figure.

A

A: Acetyl-CoA
B: Acyl-CoA
C: Malonyl-CoA
D: Acylglycerols

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34
Q

What is the name of process A/B/C/D on the scheme?

A

A: Lipogenesis
B: β-Oxidation
C: Esterification
D: Ketogenesis

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35
Q

Name the Enzyme that catalyzes the reaction.

A

Acetyl-CoA carboxylase

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36
Q

Name the Enzyme that catalyzes the reaction.

A

Biotin carboxylase

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37
Q

Name the Enzyme that catalyzes the reaction.

A

Carboxyl transferase

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38
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Ketoacyl synthase, Hydratase, Enoyl reductase, Ketoacyl reductase, Thioesterase

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39
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Malonyl/acetyl transacylase, Hydratase,
Enoyl reductase, Ketoacyl reductase, Acyl carrier protein

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40
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Ketoacyl synthase, Malonyl/acetyl transacylase, Hydratase,
Enoyl reductase, Ketoacyl reductase

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41
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Hydratase,
Enoyl reductase, Ketoacyl reductase, Acyl carrier protein, Thioesterase

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42
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer? protein, Thioesterase

A

Ketoacyl synthase, Enoyl reductase, Ketoacyl reductase, Acyl carrier protein, Thioesterase

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43
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Ketoacyl synthase, Malonyl/acetyl transacylase, Ketoacyl reductase, Acyl carrier protein, Thioesterase

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44
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Ketoacyl synthase, Malonyl/acetyl transacylase, Hydratase,
Acyl carrier protein, Thioesterase

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45
Q

What is the correct sequence of enzymes A, B, C, D and E in the primary structure of fatty acid synthase monomer?

A

Ketoacyl synthase, Malonyl/acetyl transacylase, Hydratase,
Enoyl reductase, Thioesterase

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46
Q

Name molecule A/B/C/D/E on the scheme.

A

A: Acyl(acetyl)-malonyl enzyme
B: 3-Ketoacyl enzyme (acetoacetyl enzyme)
C: D(–)-3-Hydroxyacyl enzyme
D: 2,3-Unsaturated acyl enzyme
E: Acyl enzyme

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47
Q

Name enzyme A/B/C/D/E on the scheme.

A

A: 3-Ketoacyl synthase
B: 3-Ketoacly reductase
C: Hydratase
D: Enoyl reductase
E: Thioesterase

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48
Q

Name enzyme A/B/C on the scheme.

A

A: Acetyl-CoA carboxylase
B: Malonyl acetyl transacylase
C: Malonyl acetyl transacylase

(Biosynthesis of long-chain fatty acids. Details of how addition of a malonyl residue causes the acyl chain to grow by two carbon atoms. (Cys, cysteine residue; Pan, 4′-phosphopantetheine.) The blocks highlighted in blue contain initially a C2 unit derived from acetyl-CoA (as illustrated) and subse- quently the Cn unit formed in reaction 5.)

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49
Q

Name enzyme D/E on the scheme.

A

D: 3-Ketoacyl synthase
E: 3-Ketoacyl reductase

(Biosynthesis of long-chain fatty acids. Details of how addition of a malonyl residue causes the acyl chain to grow by two carbon atoms. (Cys, cysteine residue; Pan, 4′-phosphopantetheine.) The blocks highlighted in blue contain initially a C2 unit derived from acetyl-CoA (as illustrated) and subse- quently the Cn unit formed in reaction 5.)

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50
Q

Name molecule A/B/C/D on the scheme.

A

A: Glucose-6-phosphate
B: Fructose-6-phosphate
C: Glyceraldehyde-3- phosphate
D: Pyruvate

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51
Q

Name molecule A, B, C on the scheme.

A

A: Pyruvate
B: Malate
C: Citrate

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52
Q

Name enzyme A, B, C on the scheme.

A

A: Malate Dehydrogenase
B: Glyceraldehyde-3- phosphate dehydrogenase
C: Malic Enzyme

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53
Q

Name enzyme D, E on the scheme.

A

D: ATP-Citrate lase
E: Pyruvate Dehydrogenase

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54
Q

Name enzyme F, G on the scheme.

A

F: Acetyl-CoA carboxylase
G: Isocitrate Dehydrogenase

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55
Q

Name molecule A, B on the scheme

A

A: Citrate
B: Isocitrate

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56
Q

Name molecule C, D on the scheme

A

C: Malate
D: Malonyl-CoA

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57
Q

Name Molecule A, B, C on the scheme.

A

A: Acetyl-CoA
B: Oxaloacetate
C: α-Ketoglutarate

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58
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Peripheral apoprotein
b. Cholesterol-rich lipid raft
c. Transmembrane protein
d. Cholesterol-free lipid raft

A

a. Peripheral apoprotein

59
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Phospholipid
b. Transmembrane protein
c. Free fatty acid
d. Glycerol

A

a. Phospholipid

60
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Cholesteryl ester
b. Free cholesterol
c. Phosphatidylserine
d. Cholesteryl glycerol
e. A small hydrophobic protein

A

a. Cholesteryl ester

61
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Triacylglycerol
b. Partially degraded cholesterol
c. Free fatty acid
d. Glycerol
e. A short hydrophobic peptide

A

a. Triacylglycerol

62
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Integral apoprotein
b. Cholesterol-rich lipid raft
c. Cholesterol-free lipid raft
d. Caveola

A

a. Integral apoprotein

63
Q

Examine the image. Identify “Molecule X”.

Select one:
a. Free cholesterol
b. Small hydrophobic peptide
c. Phosphatidylcholine
d. Phosphatidylserine

A

a. Free cholesterol

64
Q

Examine the image. Which is true for “Area X”?

Select one:
a. Lipoprotein core of mainly nonpolar lipids.
b. Lipoprotein core of mainly polar lipids.
c. Lipoprotein core rich in hydrophobic proteins.
d. Lipoprotein core rich in charged lipids.

A

a. Lipoprotein core of mainly nonpolar lipids.

65
Q

Examine the image. Which is true for “Area X”?

Select one:
a. Monolayer of mainly amphipathic lipids.
b. Bilayer of mainly amphipathic lipids.
c. Monolayer of mainly nonpolar lipids.
d. Bilayer of nolayer of mainly nonpolar lipids.

A

a. Monolayer of mainly amphipathic lipids.

66
Q

What is particle X?

Select one:
a. HDL
b. Chylomicron remnant
c. LDL
d. Nascent chylomicron

A

d. Nascent chylomicron

67
Q

What is particle X?

Select one:
a. Chylomicron
b. LDL
c. HDL
d. Chylomicron remnant

A

a. Chylomicron

68
Q

What is particle X (image below)?

Select one:
a. LDL
b. HDL
c. Chylomicron remnant
d. Nascent chylomicron

A

c. Chylomicron remnant

69
Q

What is particle X?

Select on:
a. HDL
b. LDL
c. VLDL
d. Chylomicron remnant

A

a. HDL

70
Q

What is particle X?

Select on:
a. HDL
b. LDL
c. VLDL
d. Chylomicron remnant

A

a. HDL

71
Q

What is enzyme X, hydrolysing the chylomicron’s triglycerides?

Select one:
a. Lipoprotein lipase
b. Phospholipase C
c. Endothelial lipase
d. Lysosomal lipase

A

a. Lipoprotein lipase

72
Q

What is molecule X?

Select one:
a. Glycerol
b. Cholesterol
c. Triglycerides
d. Phospholipids

A

a. Glycerol

73
Q

Examine the image. What is “Molecule X”?

Select one:
a. Fatty acids
b. Cholesterol
c. Phospholipids
d. Triacylglycerol
e. Cholesteryl ester

A

a. Fatty acids

74
Q

What is molecule X?

Select one:
a. Phospholipids
b. Glycerol
c. Triacylglycerol
d. Cholesterol

A

d. Cholesterol

75
Q

What is particle X?

Select one:
a. Nascent VLDL
b. Intermediate-density lipoprotein (IDL)
c. LDL
d. HDL

A

a. Nascent VLDL

76
Q

Examine the image. What is “Particle X”?

Select one:
a. VLDL
b. Intermediate-density lipoprotein (IDL)
c. LDL
d. HDL

A

a. VLDL

77
Q

Examine the image. What is “Particle X”?

select one:
a. Intermediate-density lipoprotein (IDL)
b. Nascent VLDL
c. LDL
d. HDL

A

a. Intermediate-density lipoprotein (IDL)

78
Q

Examine the image. What is “Particle X”?

Select one:
a. LDL
b. HDL
c. Intermediate-density lipoprotein (IDL)
d. VLDL

A

a. LDL

79
Q

Examine the image. What is “Particle X”?

Select one:
a. HDL
b. LDL
c. VLDL
d. Intermediate-density lipoprotein (IDL)

A

a. HDL

80
Q

Examine the image. What is “Molecule X”?

Select one:
a. Glucose
b. Fructose
c. Glucose 1,6-bisphosphate
d. Glucose 1-phosphate

A

a. Glucose

81
Q

Examine the image. What is “Hormone X”?

Select one:
a. Insulin
b. Glucagon
c. Adrenaline
d. Dopamine

A

a. Insulin

82
Q

Examine the image. What is “Molecule X”?

Select one:
a. Glucose 6-phosphate
b. Glucose 1-phosphate
c. Glucose 1,6-bisphosphate
d. Fructose 6-phosphate

A

a. Glucose 6-phosphate

83
Q

Examine the image. What are “Path X” and “Path Y”?

Select one:
a. “Path X” is Glycolysis. “Path Y” is Pentose phosphate pathway.
b. “Path X” is Pentose phosphate pathway. “Path Y” is Glycolysis.
c. Both pathways are alternative versions of Glycolysis.
d. “Path X” is Glycolysis. “Path Y” is Gluconeogenesis.
e. “Path X” is Glycogenolysis. “Path Y” is Pentose phosphate pathway.

A

a. “Path X” is Glycolysis. “Path Y” is Pentose phosphate pathway.

84
Q

Examine the image. What is “Molecule X”?

Select one:
a. Acetyl-CoA
b. Glycerol
c. Fructose
d. Cholesterol
e. Glucose

A

a. Acetyl-CoA

85
Q

Examine the image. What is “Molecule X”?

Select one:
a. Glycerol 3-phosphate
b. Glucose
c. Fructose 1,6-bisphosphate
d. Cholesterol
e. Dihydroxyacetone phosphate

A

a. Glycerol 3-phosphate

86
Q

Examine the image. What is “Molecule X”?

Select one:
a. Acyl-CoA
b. Acetyl-CoA
c. Pyruvate
d. Cholesterol
e. Glycerol

A

a. Acyl-CoA

87
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Acyl-CoA synthetase
b. Acyl-CoA lyase
c. Acyl-CoA reductase
d. Phosphoglycerate mutase
e. Hexokinase

A

a. Acyl-CoA synthetase

88
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Hormone-sensitive lipase
b. Triacylglycerol reductase
c. Glycerol synthetase
d. Fatty acid hydrolase

A

a. Hormone-sensitive lipase

89
Q

Examine the image. “Reaction X”, combining Acyl-CoA with Glycerol 3-phosphate, is a reaction of… ?

Select one:
a. Esterification
b. Oxidation-reduction
c. Etherification
d. Hydrolysis

A

a. Esterification

90
Q

Examine the image. “Reaction X”, breaking triacylglycerol (TG) into free fatty acids (FFA) and Glycerol, is a reaction of… ?

Select one:
a. Hydrolysis (Lipolysis)
b. Etherification
c. Oxidation-reduction
d. Transamination
e. Dephosphorylation

A

a. Hydrolysis (Lipolysis)

91
Q

Examine the image. What is “Molecule X”?

Select one:
a. Glycerol
b. Acyl-CoA c. Acetyl-CoA
d. Cholesterol
e. Glycogen

A

a. Glycerol

92
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Lipoprotein lipase
b. Serine hydrolase
c. Choline esterase
d. Alcohol dehydrogenase
e. Triacylglycerol ligase

A

a. Lipoprotein lipase

93
Q

Examine the image and locate the enzyme Hormone-sensitive lipase. Which compounds inhibit this enzyme?

Select one:
a. Insulin, Nicotinic acid.
b. Insulin, Glucagon.
c. Glucagon, Epinephrine.
d. Insulin, Vasopressin.
e. Epinephrine, Nicotinic acid.

A

a. Insulin, Nicotinic acid.

94
Q

Examine the image and locate the enzyme Hormone-sensitive lipase. Which compounds activate this enzyme?

Select one:
a. Glucagon, Epinephrine.
b. Glucagon, Insulin.
c. Insulin, Nicotinic acid.
d. Glucagon, Nicotinic acid.
e. Insulin, Vasopressin.

A

a. Glucagon, Epinephrine.

95
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Adenylyl cyclase
b. ATP-dependent oxidoreductase
c. AMP hydrolase
d. cAMP kinase

A

a. Adenylyl cyclase

96
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Phosphodiesterase
b. cAMP kinase
c. AMP phosphatase
d. AMP ligase

A

a. Phosphodiesterase

97
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Hormone-sensitive lipase
b. cAMP-dependent protein phosphatase
c. Triacylglycerol kinase
d. Triacylglycerol ligase

A

a. Hormone-sensitive lipase

98
Q

Examine the image. What is “Enzyme X”?

Select one:
a. cAMP-dependent protein kinase
b. cAMP-dependent protein phosphatase
c. ATP ligase
d. cAMP hydrolase

A

a. cAMP-dependent protein kinase

99
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Lipase phosphatase
b. Lipase kinase
c. Lipase hydrolase
d. cAMP-dependent protein phosphatase
e. Lipase oxidoreductase

A

a. Lipase phosphatase

100
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Hormone-sensitive lipase
b. Diacylglycerol ligase
c. Monoacylglycerol synthetase

A

a. Hormone-sensitive lipase

101
Q

Examine the image. What is “Enzyme X”?

Select one:
a. 2-Monoacylglycerol lipase
b. 2-Monoacylglycerol kinase
c. 2-Monoacylglycerol ligase
d. Glycerol synthetase

A

a. 2-Monoacylglycerol lipase

102
Q

Examine the image. What is “Molecule X”?

Select one:
a. ATP
b. ADP
c. AMP

A

a. ATP

103
Q

Examine the image. What is “Hormone X”, regulating the 3 indicated steps?

Select one:
a. Insulin
b. Glucagon
c. Adrenaline (Epinephrine)
d. Noradrenaline (Norepinephrine)
e. Testosterone

A

a. Insulin

104
Q

Examine the image. Which type of drugs could be “Molecule X”?

Select one:
a. beta-Adrenergic blockers
b. alpha-Adrenergic blockers
c. Both alpha- and beta- Adrenergic blockers

A

a. beta-Adrenergic blockers

105
Q

Examine the image. How do the 3 indicated groups of chemical compounds influence the enzyme Adenylyl cyclase?

Select one:
a. Epinephrine and Glucagon activate the enzyme; Insulin inhibits it.
b. Epinephrine and Insulin activate the enzyme; Glucagon inhibits it.
c. Nicotinic acid and TSH activate the enzyme; Norepinephrine inhibits it.
d. All activate the enzyme.
e. All inhibit the enzyme.

A

a. Epinephrine and Glucagon activate the enzyme; Insulin inhibits it.

106
Q

Examine the image. How do Adenosine and FFA (free fatty acids) influence the enzyme Adenylyl cyclase?

Select one:
a. Both inhibit the enzyme.
b. Both activate the enzyme.
c. Adenosine activates the enzyme; FFA inhibit it.
d. FFA activate the enzyme; Adenosine inhibits it.

A

a. Both inhibit the enzyme.

107
Q

Examine the image. How do the Methylxanthines influence the indicated steps?

Select one:
a. Inhibition in both cases.
b. Activation in both cases.
c. Inhibition of Phosphodiesterase; activation of the Adenosine’s effect on Adenylyl cyclase.
d. Activation of Phosphodiesterase; inhibition of the Adenosine’s effect on Adenylyl cyclase.

A

a. Inhibition in both cases.

108
Q

Examine the image. What are the 2 hormones’ effects on the indicated steps?

Select one:
a. Activation in both cases.
b. Inhibition in both cases.
c. Activation from the Thyroid hormone; inhibition from the Growth hormone.
d. Activation from the Growth hormone; inhibition from the Thyroid hormone.

A

a. Activation in both cases.

109
Q

Examine the image. What is the effect of cAMP on the cAMP-dependent protein kinase?

Select one:
a. Activation.
b. Inhibition.
c. Neither activation nor inhibition, cAMP is only a substrate for the enzyme.

A

a. Activation.

110
Q

Examine the image. What are the regulatory effects of Insulin and Thyroid hormone on the Phosphodiesterase?

Select one:
a. Positive from Insulin; negative from Thyroid hormone.
b. Positive from Thyroid hormone; negative from Insulin.
c. Positive from both.
d. Negative from both.

A

a. Positive from Insulin; negative from Thyroid hormone.

111
Q

Examine the image. What are the regulatory effects of Insulin on the indicated steps?

Select one:
a. Positive on Lipase phosphatase; negative on the cAMP-independent pathway.
b. Negative on Lipase phosphatase; positive on the cAMP-independent pathway.
c. Positive in both cases.
d. Negative in both cases.

A

a. Positive on Lipase phosphatase; negative on the cAMP-independent pathway

112
Q

Examine the image. What is “Molecule X”?

Select one:
a. Acetyl-CoA
b. Coenzyme A
c. Thiocarboxyl-CoA
d. Ethanol-CoA

A

a. Acetyl-CoA

113
Q

Examine the image. What is “Molecule X”?

Select one:
a. Acetoacetyl-CoA
b. Butanethiol-CoA
c. Glycerol-CoA
d. Coenzyme A
e. 1-methylpropanol-CoA

A

a. Acetoacetyl-CoA

114
Q

Examine the image. What is “Molecule X”?

Select one:
a. HMG-CoA reductase
b. HMG-CoA oxidase
c. HMG-CoA lyase
d. HMG-CoA hydrolase

A

a. HMG-CoA reductase

115
Q

Examine the image. What is “Molecule X”?

Select one:
a. 3-hydroxy-3-methylglutaryl- CoA (HMG-CoA)
b. 3-hydroxy-3-methylpentane- CoA
c. Acetylglycerol-CoA
d. Thiohexane-CoA
e. Butane-2-ol-acetyl-CoA

A

a. 3-hydroxy-3-methylglutaryl- CoA (HMG-CoA)

116
Q

Examine the image. What is “Molecule X”?

Select one:
a. Mevalonate
b. 3-hydroxy-3-methylpentanol
c. Hydroxymevalonic acid
d. Acetyl-acetoacetate

A

a. Mevalonate

117
Q

Examine the image. What is “Enzyme X”?

Select one:
a. Thiolase
b. CoA lyase
c. Acetase
d. Kinase

A

a. Thiolase

118
Q

Examine the image. What is “Enzyme X”?

Select one:
a. HMG-CoA synthase
b. HMG-CoA lyase
c. HMG-CoA hydrolase
d. HMG-CoA esterase

A

a. HMG-CoA synthase

119
Q

Examine the image. What is “Enzyme X”?

Select one:
a. HMG-CoA reductase
b. HMG-CoA oxidase
c. HMG-CoA lyase
d. HMG-CoA hydrolase

A

a. HMG-CoA reductase

120
Q

Examine the image. What is molecule X?

Select one:
a. Acetyl-CoA
b. Coenzyme A
c. Acetoacetyl-CoA
d. Succinyl-CoA

A

a. Acetyl-CoA

121
Q

What is molecule X?

Select one:
a. 3-methylpentane
b. Coenzyme A
c. Mevalonate
d. Isoprene

A

c. Mevalonate

122
Q

What is molecule X?

Select one:
a. Progesterone
b. Stigmasterol
c. Cholesterol
d. Testosterone

A

c. Cholesterol

123
Q

What is molecule X?

Select one:
a. Chenodeoxycholyl-CoA
b. Acetoacetyl-CoA
c. Testosteryl-CoA
d. Progesteryl-CoA
e. Vitamin D

A

a. Chenodeoxycholyl-CoA

124
Q

What is molecule X?

Select one:
a. Acetyl-CoA
b. Cholyl-CoA
c. Hydroxycholesterol-CoA
d. Cholesteryl-CoA

A

b. Cholyl-CoA

125
Q

What is molecule X?

Select one:
a. Glycocholic acid
b. Cholic acid
c. Cholesteryl-glycine

A

a. Glycocholic Acid

126
Q

What is molecule X ?

Select one:
a. Vitamin D
b. Cholic acid
c. Deoxycholic acid

A

c. Deoxycholic acid

127
Q

Examine the image. What is “Molecule X”?

Select one:
a. Lithocholic acid
b. Cholic acid
c. Vitamin D
d. Chenodeoxycholic acid

A

Answer:
a. Lithocholic acid

128
Q

What is enzyme X ?

Select one:
a. Lyase
b. Oxidase
c. Hydroxylase
d. Ligase

A

C. Hydroxylase

129
Q

What is enzyme X?

Select one:
a. Hydroxylase
b. Oxidase
c. Lyase
d. Ligase

A

a. Hydroxylase

130
Q

You can see the elongation of fatty acid chains below. Where do these reactions occur?

Select one:
a. Mitochondria
b. Cytosol
c. Nucleus
d. Endoplasmic reticulum

A

d. Endoplasmic reticulum

131
Q

You can see the microsomal fatty acid elongase system below. Which substrate S fits in the figure?

Select one:
a. Acetyl-CoA
b. Malonyl-CoA
c. Propionyl-CoA
d. Butyryl-CoA

A

b. Malonyl-CoA

132
Q

You can see the microsomal fatty acid elongase system below. Which substrate S fits in the figure?

Select one:
a. Acetyl-CoA
b. Acyl-CoA
c. Propionyl-CoA
d. Butyryl-CoA

A

b. Acyl-CoA

133
Q

You can see the elongation of fatty acid chains below. Identify the first enzyme (E1), second (E2), third (E3), fourth (E4) of the elongase system

A

E1: 3-ketoacyl-CoAsynthase
E2: 3-ketoacyl-CoA reductase
E3: 3-hydroxyl-CoA dehydrase
E4: 2-trans-enoyl-CoA reductase

134
Q

You can see the elongation of fatty acids. Identify the cofactor (C) used in the following reactions:

Select one:
a. NADH + H+
b. NAD+
c. NADPH + H+
d. NADP+
e. Both NADPH + H+ and NADH + H+ can be used
f. Both NADP+ and NAD+ can be used

A

e. Both NADPH + H+ and NADH + H+ can be used

135
Q

In the picture, you can see the regulation of an enzyme. Which enzyme is it?

Select one:
a. Acetyl-CoA carboxylase
b. Acetyl-CoA dehydrogenase
c. Malonyl-CoA decarboxylase
d. Fatty acid synthase

A

a. Acetyl-CoA carboxylase

136
Q

In the picture you can see the regulatory method of an enzyme which catalyses the first step of lipogenesis. Identify the substrate of this enzyme.

Select one:
a. Acetyl-CoA
b. Citrate
c. Propionyl-CoA
d. Oxaloacetate

A

a. Acetyl-CoA

137
Q

What product P is formed in the reaction catalyzed by Acetyl-CoA carboxylase?

Select one:
a. Malonyl-CoA
b. Propionyl-CoA
c. Citrate
d. Acetyl-carnitine

A

A. Malonyl-CoA

138
Q

In the picture you can see the regulation of the Acetyl-CoA carboxylase. Identify the missing H1 hormone.

Select one:
a. Glucagon
b. Insulin
c. Adrenalin
d. Growth hormone

A

b. Insulin

139
Q

Which molecule (L) fits in the figure?

Select one:
a. Acyl-CoA
b. Propionyl-CoA
c. Ketoacyl-CoA
d. Hydroacyl-CoA

A

a. Acyl-CoA

140
Q

Where does the following reaction occur?

Select one:
a. Mitochondria
b. Cytosol
c. Nucleus
d. Endoplasmic reticulum

A

d. Endoplasmic reticulum

141
Q

Which substrate would you choose for the following reaction?

Select one:
a. Stearoyl-CoA
b. Palmitoyl-CoA
c. Palmitoleoyl-CoA
d. Enoyl-CoA

A

a. Stearoyl-CoA

142
Q

What product (P) is formed in the following reaction?

Select one:
a. Oleoyl-CoA
b. Palmitoleoyl-CoA
c. Enoyl-CoA
d. Palmitoyl-CoA

A

a. Oleoyl-CoA

143
Q

Choose the missing enzyme.

Select one:
a. Δ9 desaturase
b. Δ4 desaturase
c. Δ5 desaturase
d. Δ6 desaturase

A

a. Δ9 desaturase

144
Q

Identify the cofactor (C) used in the following reaction.

Select one:
a. NADH + H+
b. NAD+
c. NADPH + H+
d. NADP+

A

a. NADH + H+