General Classification of drugs Flashcards

1
Q

This is achieved by:

A

Origin
Natural products
Semi synthetic
Synthetic
Therapeutic use
Chemical structure
Site of drug action
Street name

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2
Q

What is therapeutic meaning?

A

Relating to the treatment of disease or disorders by remedial agents

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3
Q

What is an adverse effect?

A

The converse and refers to harmful or undesired response.

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4
Q

What does “pure” mean?

A

The term pure means nonsynthetic.

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5
Q

How can a drug be classified by its origin?

A

Drugs that come from plants, such as the opiates, which are derived from the opium poppy.

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6
Q

How can a drug be classified by its semi syntheticity ?

A

Heroin, a semisynthetic substance, is commonly referred to as an opiate drug. Because this classification identifies solely the drug’s source,

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7
Q

How can a drug be classified by therapeutic use?

A

The method by which a medicine is utilised to treat or modify something in the body. Amphetamines, for example, are referred to be appetite suppressant medications in this system.

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8
Q

How can a drug be classified by chemical structure?

A

Barbiturates (phenobarbital, Amytal, and Seconal, for example) are synthetic chemicals created from the molecular structure of barbituric acid, the synthetic substance that serves as the chemical base for barbiturate medications.

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9
Q

How can a drug be classified by site of drug?

A

This refers to where the medicine is generating physical changes in the body. Alcohol, for example, is frequently referred to as a depressant drug due to its depressed effect on the central nervous system (CNS). Cocaine, on the other hand, is frequently referred to as a stimulant substance due to its CNS stimulating characteristics.

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10
Q

How can a drug be classified by street name?

A

This is derived from drug “subcultures” and the street drug industry.

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11
Q

Controlled Substance Analogue

A

the chemical structure of which is substantially similar to the chemical structure of a controlled substance in schedule I or II.

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12
Q

The Controlled Substances Act (CSA) was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970 has how many classification?

A

The legislation created five Schedules (classifications), with varying qualifications for a substance to be included in each.

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13
Q

What are the agencies that get to decide whether a drug is removed or added from schedules?

A

The Drug Enforcement Administration and The Food and Drug Administration

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14
Q

What are schedule I drugs?

A

substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse

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15
Q

What are examples of schedule I drugs?

A

heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.

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16
Q

What are Schedule II drugs?

A

Drugs with some medically acceptable uses, but with high potential for abuse and/or addiction. These drugs can be obtained through prescription.

17
Q

What are examples of Schedule II drugs?

A

Combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin

18
Q

What are Schedule III drugs?

A

Schedule III drugs, substances, or chemicals are defined as drugs with a moderate to low potential for physical and psychological dependence. Schedule III drugs abuse potential is less than Schedule I and Schedule II drugs but more than Schedule IV.

19
Q

What are some examples of Schedule III drugs?

A

Products containing less than 90 milligrams of codeine per dosage unit (Tylenol with codeine), ketamine, anabolic steroids, testosterone

20
Q

What are Schedule IV drugs?

A

Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence.

21
Q

What are some examples of Schedule IV drugs?

A

Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol

22
Q

What are Schedule V drugs?

A

Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics. Schedule V drugs are generally used for antidiarrheal, antitussive, and analgesic purposes.

23
Q

What are some examples of Schedule V drugs?

A

Cough preparations with less than 200 milligrams of codeine or per 100 milliliters (Robitussin AC), Lomotil, Motofen, Lyrica, Parepectolin

24
Q

How do we store controlled substances?

A

Controlled chemicals should be used and stored in specific areas (e.g., a laboratory or locked storage space allocated to a responsible party). They must be kept behind at least three (3) locks: in a locked cabinet, in a room that is locked after normal business hours, and in a locked building.

25
Q

Who will have access to controlled substances?

A

Entrance to controlled substance-containing rooms and lockable storage locations must be restricted to authorised personnel. Personnel that have been vetted properly.

26
Q

How does a lab control Inventory and Report of Loss of controlled substances?

A

Each responsible party controlled drug licence holder must implement procedures to monitor their usage of controlled substances. A thorough listing of all banned substances used, as well as a running inventory of their usage, must be included in the log book.

27
Q

In the case of reporting loss for controlled substances what is the proper protocol?

A

Authorized personnel must be vigilant for the disappearance of restricted substances and immediately report any losses to the relevant Principal Investigator, Security, Safety Office, Center Director, and Managing Director. Every year, an inventory of all controlled chemicals must be done, and a list of all substances used must be submitted to the Safety Office.

28
Q

What are the procedures for disposing waste from controlled substances in accordance with federal and state regulations and rules?

A

OPTION 1: Destruction (‘Witness Burn’)
OPTION 2: Reverse Distribution Registrant

29
Q

What does option 1: destruction (witness burn) imply for controlled substance waste disposal?

A

DEA waste compounds must be incinerated in a DEA-approved incinerator, but this option is rarely employed by researchers.

30
Q

What does option 2: Reverse Distribution Registrant imply for controlled substance waste disposal?

A

This option transfers ownership of the DEA waste substance to a DEA-approved Pharmaceutical Returns Processor for re-use, re-sale or destruction. The PI or Department must have the original registration information for each DEA substance and maintain copies of DEA Form (for Schedule I and II) or Form 41 (for Schedule III, IV, V substances) for two (2) years.

31
Q

What office is responsible for being notified of a lab/individual legally having a specific controlled drug?

A

The IBT Safety Office will notify each controlled substance license holder of the policy and require them to annually submit a list of controlled substances used and an updated list of personnel authorized to use them.