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MOD > Behavioural treatment/drugs > Flashcards

Behavioural treatment/drugs Flashcards

1
Q

What neurotransmitters do you increase to to promote biogenic amines?

A

*Catecholamines - dopamine + noradrenaline
*Serotonin

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2
Q

What neurotransmitters do you increase to promote inhibitory NT?

A

GABA

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3
Q

How can you alter neurochemistry?

A

*Medication
*Nutraceuticals
*Diet

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4
Q

When is use of medication appropriate?

A

When emotional state is inhibiting learning
-cases involving high arousal, -ve emotions (fear,anxiety,phobia), compulsive responses

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5
Q

What does drug selection depend on?

A

*Behavioural diagnosis
*Duration
*severity
*Risk of euthanasia
*Threat to animal from prescription failure

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6
Q

What are the different classes used for medication?

A

*Neuroleptics
*Azapirones
*Antidepressants
*Monoamine oxidase inhibitors
*B-blockers
*Benzodiazepines
*Anti-epileptics
*Xanthine derivatives
*Opioid antagonists
*CNS stimulants
*Antihistamines
*Hormonal preparations
*Adrenoreceptor stimulants / antagonists

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7
Q

What is an example of tricyclic antidepressant?
What would you not administer it with?

A

Clomipramine (For dogs)
Don’t administer with MAOBIs

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8
Q

What is an example of a selective serotonin reuptake inhibitor?
What would you not administer it with?

A

Fluoxetin
Don’t administer with MAOBIs

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9
Q

What is an example of a Serotonin antatgonist + reuptake inhibitor?
Is it licenced?

A

Trazadone
Not licenced for veterinary use

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10
Q

What is an example of a Monoamine oxidase B inhibitor?
What would you not administer it with?

A

Selegiline - neuroprotective
Don’t administer with pethidine, morphine, fluoxetine, phenothiazines

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11
Q

What is an example of a benzodiazepine used?
What is it used for? What are the side effects?

A

Alprazolam - (for dogs)
*memory blocking, anxiolytic + sedative
*SE = paradoxical excitement, hepatic side effects in cats + can become dependant

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12
Q

What can dexmedetomidine be used for?

A

Micro dose - anxiolytic + sedative

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13
Q

What is a beta blocker used? and what is it used for?

A

Propanolol - situational anxiety - administer 1hr before

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14
Q

What is an example of an anti-epileptic and what is it used for?

A

Imepitoin - sound related fears

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15
Q

What are hormone preparations used? M+F

A

F = Cabergoline (Galastop)
M= Deslorelin (chemical castration)

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16
Q

What are oral anxiolytics you can give cats + dogs before an appointment? When before would you use them?

A

Cats = Gabapentin / Trazadone - give orally 2-3 hours before appointment
Dogs = Trazadone / Alprazolam / Diazepam - give orally 1-2hrs before

17
Q

What drug classes are used for general anxiety?

A

*TCAs - clomipramine
*SSRIs - fluoxetine
*SARIs - Trazadone
*Anti-epileptics - Imepitoin

18
Q

What drug is used for compulsive disorders?

A

Fluoxetine - SSRI

19
Q

What drugs are used for fear related problems?

A

*MAOBI - selegiline
*Anti-epileptic - imepitoin

20
Q

What drugs are used for cognitive dysfunction?

A

*MAOBI - selegiline
*Xanthine derivative - propentofylline

21
Q

What drug is used for panic disorders leading to anxiety?

A

*SSRI - fluoxetine

22
Q

What drug is used to treat panic grief?

A

*MAOBI - selegiline

23
Q

What drugs are used to treat chronic pain?

A

Multi-modal analgesia
*NSAIDs
*Gabapentin
*Paracetamol
*NMDA antagonists

24
Q

What is phosphatidylserine used for?

A

Improves memory retrieval and exploratory behaviour

25
Q

What are the pheromones for dogs/cats that reduce stress?

A

Dog = adaptil
Cat = Feliway

26
Q

What are the common behavioural presentations seen in general practice?

A

*Firework related fear
*Feline urine in house
*Requests for neutering for behavioural reasons

27
Q

How do you prevent firework related problems?

A

*maximise emotional capacity
*Optimise drainage
*Encourage +ve behaviour
*Minimise negative behaviour + trigger salience

28
Q

How do you manage firework related problems?

A

*environmental modification - hideout (Dark & Quiet)
*pheromone support
*Don’t reassure, punish, ignore - Be passively present

29
Q

What meds can be used to manage firework related fear?

A

*Trazadone - anxiolytic + sedative
*Dexmedetomidine - micro dose - decrease arousal
*Benzodiazepines - amnesia, anxiolytic, sedative

MOD (103 decks)

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