antiemetics and antinausea

Question 1

classes of antiemetics/antinausea drugs

Answer 1

anticholinergics
antihistamines
antidopaminergic
neurokinin antagonists
prokinetic
serotonin blockers
tetrahydrocannabinoids

Question 2

question on exam: if a pt says they have an allergy to something, what do you need to know about it?

Answer 2

what is the reaction and how severe it is. also need to know whether it is an allergy or just an adverse effect

Question 3

anticholinergic drugs MOA

Answer 3

bind to and block AcH receptors in the inner ear to block transmission of nauseating stimuli

Question 4

anticholinergic drug example

Answer 4

scopolamine

Question 5

antihistamine drugs MOA

Answer 5

bind to H1 receptors

Question 6

antihistamine drug examples

Answer 6

dimenhydrinate
diphenhydramine

Question 7

antidopaminergic drug MOA

Answer 7

block dopamine receptors in CTZ

Question 8

what is the other use for antidopimanergic drug, prochlorperazine

Answer 8

intractable hiccups and psychotic disorders

Question 9

antidopaminergic drug example

Answer 9

prochlorperazine

Question 10

neurokinin receptor antagonist MOA

Answer 10

inhibit substance P/neurokinin 1 receptors in brain stem

Question 11

neurokinin receptor antagonists example

Answer 11

aprepitant

Question 12

what are two drugs that neurokinin receptor antagonists interact with

Answer 12

warfarin and birth control

Question 13

pro kinetic drug MOA

Answer 13

block dopamine receptors in CTZ and causes CTZ to be desensitized to impulses that it receives from GI tract

Question 14

pro kinetic drug example

Answer 14

metoclopramide

Question 15

serotonin blocker MOA

Answer 15

block serotonin receptors in GI tract CTZ and vomiting centre

Question 16

serotonin blocker drug example

Answer 16

ondansetron

Question 17

tetrahydrocannabinoids MOA

Answer 17

alter body’s perception of surroundings which may help relieve nausea and vomiting

Question 18

tetrahyrocannabinoids drug example

Answer 18

medical marijuana

Question 19

miscellaneous antinausea drug examples

Answer 19

aprepitant and doxylamine succinate

Question 20

herbal products drug example

Answer 20

ginger