*heart failure drugs

Question 1

what is inotropic

Answer 1

heart contraction

Question 2

what is chronotropic

Answer 2

heart rate

Question 3

what is dromotropic

Answer 3

speed of electrical impulse

Question 4

what are the symptoms of left sided heart failure

Answer 4

pulmonary edna, coughing, SOB, dyspnea, systolic= decreased contractility, diastolic= unable to relax

Question 5

what are the symptoms of right sided heart failure

Answer 5

systemic venous congestion, pedal edema, JVD, ascites, hepatic congestion

Question 6

consequences of HF

Answer 6

blood supply to organs reduced, impaired kidney filtration leads to kidney injury/failure, pulmonary edema leads to SOB and peripheral edema

Question 7

what do positive inotropic drugs do

Answer 7

increase force of contraction

Question 8

what do positive chronotropic drugs do

Answer 8

increase HR

Question 9

what do positive dromotropic drugs do

Answer 9

accelerate cardiac conduction

Question 10

what do negative inotropic drugs do

Answer 10

decrease force of contration

Question 11

what to negative chronotropic drugs do

Answer 11

decrease HR

Question 12

what do negative dromotropic drugs do

Answer 12

decrease cardiac conduction

Question 13

what are the drugs of choice for HF

Answer 13

lisinopril, valsartan and metoprolol

Question 14

when is digoxin used in regards to other medications

Answer 14

after the drugs of choice for heart failure are used

Question 15

what positive inotropic drug is used for early treatment of HF

Answer 15

dobutamine

Question 16

what drug class is lisinopril

Answer 16

ACE inhibitor

Question 17

what drugs prevents cardiac moddeling

Answer 17

lisinopril

Question 18

what drug class is valsartan

Answer 18

ARBs

Question 19

what drug class is metoprolol

Answer 19

beta blocker

Question 20

which class causes diuresis which decreases blood volume and blood return to heart

Answer 20

ACE inhibitor

Question 21

what class causes vasodilatation that decreases systemic vascular resistance

Answer 21

ARBs

Question 22

which two classes are effective in slowing ventricular remodelling and hypertrophy

Answer 22

ACE and ARBs

Question 23

which drug class stop catecholamine mediated actions on the heart

Answer 23

beta blockers

Question 24

miscellaneous drug that treats HF

Answer 24

dobutamine

Question 25

phosphodiesterase inhibitors MOA

Answer 25

inhibits the enzyme phosphodiesterase to have a positive inotropic effect

Question 26

what drug class is milrinone

Answer 26

phosphodiesterase inhibitors

Question 27

what duration of time is milrinone not supposed to be used for

Answer 27

long term use

Question 28

what cannot be administered IV with milrinone

Answer 28

furosemide

Question 29

what is the prototype of cardiac glycosides

Answer 29

digoxin

Question 30

what is the MOA of cardiac glycosides

Answer 30

increase myocardial contractility by changing the electrical conduction properties of the heart

Question 31

what type of effect does digoxin have on the heart (one of the three effects)

Answer 31

positive inotropic effect

Question 32

what indicates digoxin toxicity

Answer 32

most adverse effects signs and symptoms

Question 33

what is digoxin immune fab therapy used for

Answer 33

hyperkalemia, cardiac dysthymias and digoxin overdose

Question 34

what food in large amounts negatively effects the absorption of oral digoxin

Answer 34

bran

Question 35

what reduces digoxin levels

Answer 35

ginseng, hawthorn and st johns wort