Enzymes And Muscles

Question 1

Large animal enzyme chemistry

Answer 1

GGT
AST
CK
SDH

Question 2

Small animal chemistry

Answer 2

ALT
ALP

Question 3

Leakage enzymes

Answer 3

AST, CK, ALT, SDH, LDH, AMS, LPS

Question 4

Induction enzymes

Answer 4

GGT ALP

Question 5

Causes for enzyme increase

Answer 5

Hemolysis & lipemia
- renal disease : AMS & LPS
Hyperplasia
- L-GGT & B-ALP
Ingestion - colostrum GGT

Question 6

Features of creatine kinase

Answer 6

Short half life, correlates w severity of damage

Question 7

Causes for elevated CK

Answer 7

Rhabdomyolysis
- capture myopathy
- Exertional myopathy
Recumbence - LA
Hemolysis
Young age
Seizures/strenuous activity
Selenium deficiency

Question 8

Causes for AST increase

Answer 8

Muscle, hepatic, cardiac injury
Longer half life
Resolution - v CK ^ AST
Ongoing disease - ^ CK ^ AST

Question 9

Features of ALT

Answer 9

Long half life
Liver specific is SA
Hemolysis + muscle injury can elevate
Anticonvulsants + steroids great increase
Hyperthyroidism in cats ^^^

Question 10

Myoglobin vs hemoglobin

Answer 10

Hemo - red plasma = hemoglobinuria
Myo - normal plasma = myoglobinemia

Question 11

Other chemistry markers for muscle injury

Answer 11

Hyperkalemia
Hypoatremia
Hypochorlidemia
Hyperphosphatemia
Hypocalcemia