BB2 Anatomy2 Flashcards

1
Q

Looking at the axial CT images carefully, you see mass which has taken up the contrast and appears bright. Which of these cerebral cortical regions does this mass overlie?

Prefrontal cortex
Auditory cortex
Primary motor cortex
Visual cortex

A

Looking at the axial CT images carefully, you see mass which has taken up the contrast and appears bright. Which of these cerebral cortical regions does this mass overlie?

Prefrontal cortex
Auditory cortex
Primary motor cortex
Visual cortex

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2
Q

According to a colleague of Marina - Lydia - who witnessed the event, the seizure was preceded by abnormal, repetitive movements. Looking again at the coronal view of the CT brain (below) and recalling the motor homunculus, in which body part would these abnormal movements most likely be observed:

Right face
Left face
Right upper limb
Left upper limb
RIght lower limb
Left lower limb

A

According to a colleague of Marina - Lydia - who witnessed the event, the seizure was preceded by abnormal, repetitive movements. Looking again at the coronal view of the CT brain (below) and recalling the motor homunculus, in which body part would these abnormal movements most likely be observed:

Right face
Left face
Right upper limb
Left upper limb
RIght lower limb
Left lower limb

The mass is probably closest to the upper limb region of the primary motor cortex. The lower limb is represented more medially and the face is represented more laterally.

Of course, the problem is in the right hemisphere, so this will manifest on the left side peripherally.

Clinically, this phenomenon of abnormal, unprovoked sensorimotor activity is known as a focal or partial seizure, and reflects involvement of distinct funtional areas of cortex.

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3
Q

Lydia adds that after 30-60 seconds of these abnormal movements, Marina lost consciousness, fell to the floor, and her whole body started tensing and shaking violently. What does this represent, anatomically? [1]

A

Acceptable responses: generalised seizure, tonic clonic seizure, tonic-clonic seizure, secondary generalised seizure, generalised tonic clonic seizure, global cortical involvement

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4
Q

An aneurysm is defined as swelling of a vessel [] times greater than the normal diameter

A

An aneurysm is defined as swelling of a vessel 1.5 times greater than the normal diameter

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5
Q

Which of the following is the right common carotid artery

A
B
C
D
E
F

A

Which of the following is the right common carotid artery

A
B
C
D
E
F

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6
Q

Which of the following is the left internal carotid artery

A
B
C
D
E
F

A

Which of the following is the left internal carotid artery

A
B
C
D
E
F

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7
Q

Which of the following is the left vertebral artery

A
B
C
D
E
F

A

Which of the following is the left vertebral artery

A
B
C
D
E
F

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8
Q

Through which foramen do the internal carotid arteries (ICA) enter the skull?

Foramen lacerum
Carotid canal
Foramen rotundum
Foramen magnum

A

Through which foramen do the internal carotid arteries (ICA) enter the skull?

Foramen lacerum
Carotid canal
Foramen rotundum
Foramen magnum

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9
Q

Which of the following is predominately filled with cartliage?

Foramen lacerum
Carotid canal
Foramen rotundum
Foramen magnum

A

Which of the following is predominately filled with cartliage?

Foramen lacerum
Carotid canal
Foramen rotundum
Foramen magnum

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10
Q

A 22-year-old man sustains a blunt-force head injury and briefly loses consciousness. CT head finding shows a skull base fracture involving the foramen in the middle cranial fossas, traversed by the internal carotid artery. Which of the following nerves travels through this foramen?

A. Maxillary
B. Greater petrosal
C. Nerve to stapedius
D. Posterior auricular

A

A 22-year-old man sustains a blunt-force head injury and briefly loses consciousness. CT head finding shows a skull base fracture involving the foramen in the middle cranial fossas, traversed by the internal carotid artery. Which of the following nerves travels through this foramen?

A. Maxillary
B. Greater petrosal
C. Nerve to stapedius
D. Posterior auricular

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11
Q

A 70-year-old male presented to the emergency department complaining of blurred vision on his right eye. CT angiogram shows an embolus on the right ophthalmic artery. By which route would an embolus most likely reach the ophthalmic artery?

A. Internal carotid canal – foramen rotundum – cavernous sinus to medial anterior clinoid process

B. Internal carotid canal – foramen lacerum – cavernous sinus to medial anterior clinoid process

C. Internal carotid canal – foramen lacerum – cavernous sinus lateral to anterior clinoid process

D. Internal carotid canal – foramen spinosum – cavernous sinus medial to anterior clinoid process

A

A 70-year-old male presented to the emergency department complaining of blurred vision on his right eye. CT angiogram shows an embolus on the right ophthalmic artery. By which route would an embolus most likely reach the ophthalmic artery?

A. Internal carotid canal – foramen rotundum – cavernous sinus to medial anterior clinoid process

B. Internal carotid canal – foramen lacerum – cavernous sinus to medial anterior clinoid process

C. Internal carotid canal – foramen lacerum – cavernous sinus lateral to anterior clinoid process

D. Internal carotid canal – foramen spinosum – cavernous sinus medial to anterior clinoid process

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12
Q

Through which foramen do the vertebral arteries enter the skull?

Foramen lacerum
Hypoglossal canal
Jugular foramen
Foramen magnum

A

Through which foramen do the vertebral arteries enter the skull?

Foramen lacerum
Hypoglossal canal
Jugular foramen
Foramen magnum

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13
Q

A 58-year-old man presents to the clinic with three months of progressively worsening headaches and balance problems. An MRI reveals a circumscribed extra-axial homogenous mass compressing the foramen shown in the image (red arrow). Which one of the following nerves passes through this foramen?

A. Glossopharyngeal
B. Vagus
C. Accessory
D. Hypoglossal

A

A 58-year-old man presents to the clinic with three months of progressively worsening headaches and balance problems. An MRI reveals a circumscribed extra-axial homogenous mass compressing the foramen shown in the image (red arrow). Which one of the following nerves passes through this foramen?

A. Glossopharyngeal
B. Vagus
C. Accessory
D. Hypoglossal

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14
Q

A 58-year-old man presents to the clinic with three months of progressively worsening headaches and balance problems. An MRI reveals a circumscribed extra-axial homogenous mass compressing the foramen shown in the image (red arrow). Which one of the following nerves passes through this foramen?

A. Glossopharyngeal
B. Vagus
C. Accessory
D. Hypoglossal

A

A 58-year-old man presents to the clinic with three months of progressively worsening headaches and balance problems. An MRI reveals a circumscribed extra-axial homogenous mass compressing the foramen shown in the image (red arrow). Which one of the following nerves passes through this foramen?

A. Glossopharyngeal
B. Vagus
C. Accessory
D. Hypoglossal

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15
Q

A 65-year-old female presents to the clinic for a follow-up of a long history of refractory headaches. The pain is transmitted via a branch of the mandibular division of the trigeminal nerve that supplies sensory input to the dura mater. From the image shown, through which opening does the corresponding nerve enter the skull?

A
B
C
D

A

A 65-year-old female presents to the clinic for a follow-up of a long history of refractory headaches. The pain is transmitted via a branch of the mandibular division of the trigeminal nerve that supplies sensory input to the dura mater. From the image shown, through which opening does the corresponding nerve enter the skull?

A
B
C
D

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16
Q

What kind of haemorrhage is shown?

Extradural haemorrhage
Subarachnoid haemorrhage
Subdural haemorrhage

A

What kind of haemorrhage is shown?

Extradural haemorrhage
Subarachnoid haemorrhage
Subdural haemorrhage

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17
Q

Which vessel is most likely to have ruptured?

A

Right MCA

The right middle cerebral artery is the most likely to have ruptured in this scenario, as this travels out laterally to supply the lateral region of the cortex.

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18
Q

Based on the appearances on the imaging and the vessel most likely to have been affected, what symptoms might the patient experience? Tick all that apply. [2]

A

Left sided upper limb paraesthesia and weakness

The haemorrhage is in the region of the right middle cerebral artery. Applying the knowledge we have of the homunculus and the regions which the vasculature supply, we can try and make sense of the symptoms the patient may experience.

We know there is cross over, and as the bleed is on the right-hand side of the brain, the left-hand side of the body will be affected.

We know that the MCA has been affected, and that this supplies the lateral portion of the brain including the primary motor cortex (pre-central gyrus) and primary somatosensory cortex (post-central gyrus). This more lateral region of the brain (if we think back to the homunculus), is responsible for the trunk, upper limb and face. Therefore, of the symptoms listed, the patient is most likely to have left-sided upper limb paraesthesia and left-sided upper limb weakness.

Aphasia is less likely in this case, as Broca’s area (responsible for expressive speech) is most commonly found on the left hemisphere, along with Wernicke’s area (responsible for receptive speech).

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19
Q

Sometimes, the blood can irritate the layers of the meninges disturbing the arachnoid granulations and flow of CSF. Clots can also occasionally form after certain types of intracranial bleeds. Both of these can lead to swelling of the ventricles due to lack of absorption or obstruction.

What is the name of the condition where the ventricles within the brain enlarge?

A

Acceptable responses: Hydrocephalus, Communicating hydrocephalus, Non-communicating hydrocephalus, Obstructive hydrocephalus

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20
Q

diencephalon is a collection of grey matter structures in the forebrain, found between the telencephalon and the mesencephalon.

It includes a number of very important subcortical structures. These are:[4]

A

Thalamus
Hypothalamus
Epithalamus
Subthalamus

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21
Q

Thalamus: lies either side of the []

A

Thalamus: lies either side of the lateral ventricles

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22
Q

The only sensory information to bypass the thalamus is [] information,

Olfactory
Oplthalmic
Proprioception
Audiology

A

The only sensory information to bypass the thalamus is [] information, which travels directly to olfactory cortex

Olfactory
Oplthalmic
Proprioception
Audiology

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23
Q

Which of the following thalamic nuclei is involved with hearing

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with hearing

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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24
Q

Which of the following thalamic nuclei is involved with memory

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with memory

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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25
Q

Which of the following thalamic nuclei is involved with motor input from cerebellum

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with motor input from cerebellum

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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26
Q

Which of the following thalamic nuclei is involved with motor input from basal ganglia

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with motor input from basal ganglia

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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27
Q

Which of the following thalamic nuclei is involved with vision

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with vision

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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28
Q

Which of the following thalamic nuclei is involved with touch, pain, pressure & proprioception

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following thalamic nuclei is involved with touch, pain, pressure & proprioception

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

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29
Q

The epithalamus has two main components. What are they? [2]

A

Pineal gland
Habenular nuclei

Habenular

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30
Q

Which hormone does the pineal gland secrete and what is its function? [2]

A

secretesmelatonin;
which regulates circadian rhythm.

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31
Q

Which of the following is the pineal gland?

A
B
C
D
E

A

Which of the following is the pineal gland?

A
B
C
D
E

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32
Q

Which of the following is the pineal gland? [1]

A
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33
Q

Having revised the anatomy of the diencephalon, you have another look at Christina’s imaging and notice a mass. From which structure is this mass arising?

Hypothalamus
Pituitary
Thalamus
Pineal gland

A

Having revised the anatomy of the diencephalon, you have another look at Christina’s imaging and notice a mass. From which structure is this mass arising?

Hypothalamus
Pituitary
Thalamus
Pineal gland

The pituitary gland appears moderately enlarged - this is more noticeable on the axial and coronal views. Here, we can see it filling the sella turcica, and we can see the hypothalamus displaced superiorly.

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34
Q

You examine Christina’s visual fields and discover that there is indeed a visual field defect. Involvement of which structure is most likely to be responsible for this defect? [1]

A

Acceptable responses: optic chiasm, chiasm

35
Q

Which thalamic nucleus receives input from the optic tract?

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

36
Q

Which of the following is A

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

A

Which of the following is A

Lateral geniculate nucleus (LGN)
Medial geniculate nucleus (MGN)
Ventral posterior lateral nucleus (VPL)
Anterior nucleus (A)
Ventral lateral nucleus (VL)
Ventral anterior nucleus (VA)

37
Q

After completing your full examination, you think that Christina’s hands are larger than you would expect for her size. You also agree that her facial features have changed slightly compared to pictures from a year ago. Excess of which pituitary hormone may be responsible for these changes? [1]

A

Acceptable responses: growth hormone, GH, Somatotropin

The description of the wedding band no longer fitting is classic for a history of acromegaly

38
Q

State what the blue arrow is pointing to [1]

Which part of the brain is it in? (pons, medulla or brainstem?)

A

Substantia nigra: in midbrain

39
Q

Which cranial nerve exits the posterior surface of the midbrain?

Olfactory
Optic
Oculomotor
Trochlear

A

Which cranial nerve exits the posterior surface of the midbrain?

Olfactory
Optic
Oculomotor
Trochlear

The trochlear nerve is the only nerve to exit the brainstem posteriorly, and can be seen on the image above wrapping around the brainstem.

40
Q

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

A

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

41
Q

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

A

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

42
Q

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

A

Which structure is the arrow pointing?

Thalamus
Global pallidus
Internal capsule
Caudate nucleus
Putamen

43
Q

Graham sees a neurologist who diagnosed him with Parkinson’s disease and prescribed with []

A

Graham sees a neurologist who diagnosed him with Parkinson’s disease and prescribed with levodopa

44
Q

Atrophy of which component of the basal ganglia is responsible for Graham’s Parkinsonian symptoms?

Putamen
Caudate
Globus pallidus
Substantia nigra

A

Atrophy of which component of the basal ganglia is responsible for Graham’s Parkinsonian symptoms?

Putamen
Caudate
Globus pallidus
Substantia nigra

45
Q

Label A-E

A

A: caudate
B: putamen
C: thalamus
D: internal capsule
E: substantia nigra

46
Q

Which component of the basal ganglia appears smaller than usual in this image?

A: caudate
B: putamen
C: thalamus
D: internal capsule
E: substantia nigra

A

Which component of the basal ganglia appears smaller than usual in this image?

A: caudate
B: putamen
C: thalamus
D: internal capsule
E: substantia nigra

47
Q

Where does the reticular formation send information to?

A

output to the cerebral cortex, hypothalamus, cerebellum, ventral horn cells in the spinal cord; sympathetic and parasympathetic outflows.

(Reticular means net-like, and the reticular formation is so-called due to its connections throughout the central nervous system)

48
Q

The reticular formation filters out sensory information via which system? [1]

A

Due to its many connections, it has many functions, including regulation of skeletal muscle, regulation of autonomic function, ‘filtering’ of sensory information and even maintenance of consciousness. The latter is particularly controlled by the ascending reticular activating system (aRAS) which relays sensory information to the cerebral cortex.

49
Q

What is the name for this system? [1]

A

Reticular activating system

50
Q

A 76-year old male in a senior facility was brought to his provider due to difficulty sleeping for 6 months. His wife died two months ago and aggravated further his sleep problem. Regulation of his sleep cycle and control of consciousness is a function of which of the following?
A. Reticular formation
B. Hypothalamus
C. Basal ganglia
D. Pineal gland

A

A 76-year old male in a senior facility was brought to his provider due to difficulty sleeping for 6 months. His wife died two months ago and aggravated further his sleep problem. Regulation of his sleep cycle and control of consciousness is a function of which of the following?
A. Reticular formation
B. Hypothalamus
C. Basal ganglia
D. Pineal gland

51
Q

Describe the link between PD and the RF [1]

A

Patients with both Parkinson disease have been shown to have degeneration of the reticular activating system, particularly decreased density of neurons in the locus coeruleus, contributing to the progression of Parkinson disease.

52
Q

The majority of the reticular formation is [excitatory or inhibitory]?

A

The majority of the reticular formation is excitatory.

53
Q

Functionally, the limbic system is responsible for [5]

A

Functionally, the limbic system is responsible for olfaction, emotion, behaviour, motivation and memory

54
Q

After the olfactory nerve rootlets have passed through the cribiform plate and synapsed in the olfactory bulb, which olfactory tracts does olfactory information travel in?

Where do these tracts travel to? [2]

A

Olfactory tracts divide into into lateral and medial striae

The lateral stria continues to the primary olfactory cortex, which resides within the uncus.

The medial stria carries fibres to the contralateral olfactory bulb via the anterior commissure

55
Q

During cadaveric dissection of the anterior cranial fossa, 20 small nerve bundles are seen emerging from the foramen of the cribriform plate that converges on the olfactory bulb. Which of the following embryological structures do these nerve bundles extend from?

A. Myelencephalon
B. Metencephalon
C. Forebrain
D. Mesencephalon

A

During cadaveric dissection of the anterior cranial fossa, 20 small nerve bundles are seen emerging from the foramen of the cribriform plate that converges on the olfactory bulb. Which of the following embryological structures do these nerve bundles extend from?
A. Myelencephalon
B. Metencephalon
C. Forebrain
D. Mesencephalon

56
Q

Explain why there is a strong link between smell & emotion [2]

A

The primary olfactory cortex sends projections widely throughout the limbic system, including the hippocampus and amygdala

57
Q

The hippocampus is an infolding of the medial [] lobe into the lateral ventricle, and has roles in episodic memory.

Parietal
Frontal
Temporal
Occipital

A

The hippocampus is an infolding of the medial [] lobe into the lateral ventricle, and has roles in episodic memory.

Parietal
Frontal
Temporal
Occipital

58
Q

The hippocampus is associated with what type of memory? [3]

A

episodic memory: autobigraphical memory of past events
new memory formation
spatial navigation

59
Q

Hippocampal associations

Label A & B [2]

A

A: Dentate gyrus
B: parahippocampal gyrus

60
Q

Label A-C

A

A: Amygdala
B: Hippocampus
C: Parahippocampal cortex

61
Q

Label A-F

A

A: parahippocampal gyrus
B: fornix
C: anterior thalamic nucleus
D: cingulate nucleus
E: mammillary body
F: hippocampus

62
Q

The cingulate gyrus is continuous with the parahippocampal gyrus inferiorly, and is connected via a white matter tract known as the []

A

The cingulate gyrus is continuous with the parahippocampal gyrus inferiorly, and is connected via a white matter tract known as the cingulum

62
Q

The cingulate gyrus is continuous with the parahippocampal gyrus inferiorly, and is connected via a white matter tract known as the []

A

The cingulate gyrus is continuous with the parahippocampal gyrus inferiorly, and is connected via a white matter tract known as the cingulum

63
Q

Label A-J

A

a, cingulum;
b, cingulum fibres entering parietal cortex;
c, corpus callosum;
d, head of caudate nucleus;
e, body of the fornix;
f, columns of the fornix;
g, mammillary body;
h, mammillothalamic tract;
i, anterior nucleus of the thalamus;
j parahippocampus

64
Q

The most notable structure involved in emotion is the

hippocampus
hypothalamus
cingulate gyrus
pineal gland
amygdala

A

The most notable structure involved in emotion is the

hippocampus
hypothalamus
cingulate gyrus
pineal gland
amygdala

65
Q

Where does the amygdala connect to? [6]

A

Hippocampus: emotional coding of memory

Hypothalamus : effect the autonomic responses to emotion

Thalamus, the cingulate gyrus and the septal nuclei

Prefrontal and orbital frontal cortex,

olfactory bulb

65
Q

Where does the amygdala connect to? [6]

A

Hippocampus: emotional coding of memory

Hypothalamus : effect the autonomic responses to emotion

Thalamus, the cingulate gyrus and the septal nuclei

Prefrontal and orbital frontal cortex,

olfactory bulb

66
Q

Which of the following structures looks atrophied

Thalamus
Brainstem
Amygdala
Hippocampal formation
Pituitary

A

Which of the following structures looks atrophied

Thalamus
Brainstem
Amygdala
Hippocampal formation
Pituitary

67
Q

Medial temporal love atrophy is typical of

Alzheimers Disease
Parkinsons
Depression
Schizophrenia
Huntingdons Disease

A

Medial temporal love atrophy is typical of

Alzheimers Disease
Parkinsons
Depression
Schizophrenia
Huntingdons Disease

causes a loss of the hippocampus

68
Q

Which of the following would most likely be cause from damage to the hippocampus?

Loss of procedural memory
Anterograde amnesia
Impaired spatial cognition
Retrograde amnesia
Imparied attention

A

Which of the following would most likely be cause from damage to the hippocampus?

Loss of procedural memory
Anterograde amnesia
Impaired spatial cognition

Hippocampus is vital for navigation in space and for forming ‘mental maps’ - this explains why patients with Alzheimer’s Disease commonly get lost even in familiar environments

Retrograde amnesia
Imparied attention

69
Q

Lorraine describes her father’s recent behavioural changes in more detail: he seems uninterested in doing things, is missing bills, and does not seem to enjoy playing with his great grandchildren as he usually did.

Wich part of the brain is most likely affected?

Cingulate cortex
Hypothalamus
Thalamus
Hippocampus
Mamillary bodies

A

Cingulate cortex

Many types of behavioural changes are common in Alzheimer’s Disease, but this picture suggests apathy, characterised by poor motivation and altered affect (this also commonly coexists with depression). This suggests involvement of the cingulate cortex (probably anterior cingulate cortex) as well as the prefrontal and orbital frontal cortex.

70
Q

Lorraine is worried that Thomas may also become aggressive as this happened to her friend’s mother, who had Alzheimer’s Disease. Which part of the brain is associated with anger and fear?

A

Acceptable responses: Amygdala, amygdaloid nucleus

71
Q

Alzheimer’s Disease may also be associated with altered perception of sensation and attention. Which structure, responsible for relaying information from ascending tracts to the neocortex, may be involved? [1]

A

Acceptable responses: reticular formation

72
Q

The superior cerebellar peduncles connect the cerebellum to the [] and carry outputs from the cerebellum to the []

The middle cerebellar peduncles carry input to the cerebellum from the []

The inferior cerebellar peduncle carry input to the cerebellum from the [] conveying sensory information to the cerebellum from muscle proprioceptors of the body and sensory information concerned with equilibrium and balance from the [] via brain stem relays.

A

The superior cerebellar peduncles connect the cerebellum to the midbrain and carry outputs from the cerebellum to the cerebral cortex via relay in the thalamus

middle cerebellar peduncles carry input to the cerebellum from the pons

The inferior cerebellar peduncle carry input to the cerebellum from the medulla oblongata conveying sensory information to the cerebellum from muscle proprioceptors of the body and sensory information concerned with equilibrium and balance from the inner ear via brain stem relays.

73
Q

Which of the following is the middle cerebellar peduncle

A
B
C
D
E

A

Which of the following is the middle cerebellar peduncle

A
B
C
D
E

74
Q

Which of the following is the tonsil

A
B
C
D
E

A

Which of the following is the tonsil

A
B
C
D
E

75
Q

Which of the following is the floccus

A
B
C
D
E

A

Which of the following is the floccus

A
B
C
D
E

76
Q

Which of the following is the inferior cerebellar peduncle

A
B
C
D
E

A

Which of the following is the inferior cerebellar peduncle

A
B
C
D
E

77
Q

Which of the following is the arbor vitae?

A
78
Q

There are two kinds of motor symptoms after cerebellar injury. Explain what they are [2]

A
  1. HYPOTONIA –manifests as muscle weakness and loss of motor tone. It results in a floppy, loose-jointed, rag-doll like appearance with pendular reflexes and the patient appears “drunk”.
  2. ATAXIA - which manifests as “errors in the rate, range or force of movement”
79
Q

What are they signs and symtpoms of cerebellar pathology? [6]

A

DANISH

Dysdiadochokinesia, ataxia, nystagmus, intention tremor, scanning dysarthria, hypotonia

80
Q

Which toxin particularly effects the cerebellum

Cocaine
MDMA
Heroin
Nicotine
Alcohol

A

Which toxin particularly effects the cerebellum

Cocaine
MDMA
Heroin
Nicotine
Alcohol

81
Q

Name the 3 most common paediatric brain tumours [3]

A
  1. Astrocytoma (30%). Most frequently located in the cerebellar hemisphere. Can be surgically removed with good morbidity.
  2. Medulloblastoma (20%) Malignant and arise from granular layer of cerebellar cortex. Invade 4th ventricle and can block CSF flow.
  3. Ependymoma (15%) Occur in 4th ventricle and obstruct CSF flow.
82
Q

Name the 3 most common paediatric brain tumours [3]

A
  1. Astrocytoma (30%). Most frequently located in the cerebellar hemisphere. Can be surgically removed with good morbidity.
  2. Medulloblastoma (20%) Malignant and arise from granular layer of cerebellar cortex. Invade 4th ventricle and can block CSF flow.
  3. Ependymoma (15%) Occur in 4th ventricle and obstruct CSF flow.