Inflammatory Bowel Disease

Question 1

What are the environmental factors of IBD?

Answer 1

NSAID
Smoking ( for Crohn’s)
Infection/Antibiotics
Diet

Question 2

Ulcerative Colitis manifests only where?

Answer 2

Rectum, Colon and mucosa
NOT the whole wall of the colon

Question 3

For UC, what are the most common symptoms?

Answer 3

Rectal bleeding/Bloody Diarrhea
Cramping, constant fecal urgency, passage of mucous

Question 4

What is involved in Crohn’s disease?

Answer 4

All layers of bowel wall
All parts pf gastrointestinal tract (mouth to anus)

Question 5

What are skin lesions in endoscopy?

Answer 5

Deep linear ulceration that are separated by normal mucosa.

Question 6

What are the differential diagnosis of IBD?

Answer 6

infection diarrhea
bowel ischemia
small bowel lymphoma
diverticulitis
appendicitis
drugs
celiac sprue
IBS

Question 7

In IBD: which laboratory testing should be included?

Answer 7

CBC
ESR
Stool Studies
Cultures

Question 8

What is the most common extra intestinal manifestation?

Answer 8

Rheumatoid Arthritis!

Question 9

What is the most life threatening complication of IBD?

Answer 9

Toxic Megacolon

Question 10

What is the most common complication in IBD?

Answer 10

Fistulas

Question 11

Which drug is the main treatment for UC and CD?

Answer 11

5-aminosalicylate

Question 12

What is necessary to evaluate a risk in ulcerative colitis?

Answer 12

1. Extent and severity of the disease
2. age at disease onset
3. date of last attack
4. current therapy
5. extra intestinal manifestation
6. type and extent of any surgery

Question 13

What is necessary to evaluate risk in Crohn’s disease?

Answer 13

1. age of onset
2. date of the last exacerbation
3. treatment medications
4. surgical history
5. extent and severity of disease
6. complications including malabsorption
7. presence of any extra intestinal manifestation
8. indication of how the individual functions in his daily life