Ch.35 Jejunum and Ileum Flashcards

1
Q

Length of small intestine

A

10 - 30 meters average 25m

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2
Q

Length of jejunum

A

17 - 28 meters

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3
Q

Where is the jejunum located

A

Left dorsal abdomen between loops of SC

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4
Q

Arterial supply of jejunum

A

Cranial mesenteric artery

Major jejunal artery ->arcuate vessel forms a loop with next major jejunal vessel

Vasa recta -> from arcuate vessel to intestinal wall

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5
Q

Venous drainage

A

Portal v

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6
Q

Length of ileum

A

0.7 meters

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7
Q

Arterial supply to ileum

A

Ileal artery a branch from the iliocecocolic artery -off of cranial mesenteric

Travels along ileum -> anastomoses with last jejunal artery

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8
Q

Describe the 3 layers of muscle of the ileocecal papilla

A
  1. Inner circular
  2. Central longitudinal layer from ileum
  3. Outer from circular m of cecum
    arranged into semi circular lips
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9
Q

When does the true ileocecal sphincter contract

A

In sync with contractions of the cecal base

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10
Q

Where does digestion and absorption of nutrients take place

A

Upper half of the small intestine

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11
Q

What surrounds each villus

A

6-9 crypts of Lieberkuhn

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12
Q

Describe the mucosal folds and place circulates in the small intestine

A

Ha doesn’t have any

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13
Q

What makes up 90% of the small intestine epithelial cells

A

Columnar absorptive cells or enterocytes

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14
Q

What makes up the remaining 10% of small intestine epithelial cells

A

Mucous (goblet) cells
Enteroendocrine cells
Paneth cells
Undifferentiated columnar cells

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15
Q

Describe the activity of the columnar cells of the villi

A

After 2 divisions in the crypt they move to the villus as adult absorptive cells
Eventually extruded at the villi tip
Turnover time of 2-3 days

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16
Q

How is the apical surface of mature enterocytes arranged

A

In to Microvilli - form a brush border membrane

17
Q

Where are the enzymes of digestion of carbs, proteins and specific transport systems for absorbing end products located

A

In the microvilli

18
Q

How are the pancreas and liver stimulated to secrete bicarb and water

A

hydrogen ions in the duodenum -> release of secretin from S-cells in the duodenal mucosa

19
Q

Protein and fat in the duodenum stimulate the release of what

A

CCK - Cholecystokinin from I-cells in the duodenal mucosa

20
Q

Effect of CCK release from the duodenal mucosa

A

Causes Pancreas to secrete
1. Amylase (carbs)

  1. Lipase (fat)
  2. Trypsin, chemotrypsin,
    carboxypeptidase, elastic (protein)
  3. Co-lipase (coenzymes)
21
Q

How is Tripsinogen production integral to digestion

A

Tripsinogne is precursor (zymogen) to trypsin

Trypsinogen needs to reach SI to be activated to Trypsin by brush border enzyme enterokinase

Other enzymes secreted as zymogens can only be activated by trypsin

22
Q

What volume of enzymatic secretion are produced by horses

A

10-12L/100kg BW per day

23
Q

What uniquely has a marked secretory response on the pancreas in horses

A

Gastrin

24
Q

What is the main inorganic anion in the horse’s pancreatic secretions

A

Cl-

25
Q

Some starch fermentation in horses uniquely occurs where

A

Stomach and SI

26
Q

Almost complete digestion of starch from what food source occurs in the small intestine

A

oats and wheat

27
Q

What forms conjugated bile salts

A

Cholic acid & Chenodeoxycolic acid
combine with
Glycine & Taurine

28
Q

What are bile salts required for in the SI

A

Emulsification of fat

29
Q

Describe enterohepatic circulation of bile

A

94% of bile salts are absorbed in the SI pass to the liver and are re-secreted

30
Q

Where are bile salts at their highest concentration

A

Prox jejunum

31
Q

Where in the SI is most water absorbed

A

Distal 1/3

32
Q

What is solvent drag

A

Water movement from lumen into plasma through cell will drag permeant ions - sugars, amino acids, Ca2+ and Mg2+ with it.