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Endocrine > Endocrine Pharm: MOA and AE > Flashcards

Endocrine Pharm: MOA and AE Flashcards

1
Q

What are the growth hormone drugs?

A

Somatotropin (hGH)
Somatrem (hGH + 1 methionine)
IGF-1 or somatomedin C (hIGF-1)-mescermin

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2
Q

What are the growth hormone antagonists?

A

Pegvisomant

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3
Q

What are the somatostatin analogs?

A

Octreotide

Lanreotide

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4
Q

What are the dopamine receptor agonists to decrease prolactin?

A

Cabergoline

Bromocriptine

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5
Q

What are other growth inducing drugs?

A 
Thyrotropin (TSH)
LH
FSH
Menotropin
recombinant FSH=follitropin alpha
Follitropin Beta
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6
Q

What are thyroid drugs?

A

Levothyrocine=T4
Liothyronine sodium=T3
Liotrix=T4/T4 mixture

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7
Q

What drug is a T4/T3 mixture?

A

Liotrix

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8
Q

What drug is just T3?

A

Liothyronine sodium

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9
Q

What drug is just T4?

A

Levothyroxine

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10
Q

What drugs inhibit thyroid?

A

PTU: propylthiouracil
Methiomzole
Potassium Iodine
Radioactive iodine

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11
Q

What are the non human insulins?

A

beef
pork
sheep

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12
Q

What are the modifide crystal size insulins?

A 
NPH insulin
NPH/Reg (50/50)
NPH/reg (70/30)
Lente
Semilente
Ultralente
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13
Q

What ar the synthetic human insulins and analogs?

A 
Recominant human insulin (humulin)
Human  insulin made by swithcing aa of pork insulin (Novolin)
Insulin:
     Lispro
     Aspart
     Glarnine
     Detemir
     Glulisine
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14
Q

What are the classes of drugs for type II diabetes?

A 
StAB Mellitus: 
Sulfonylureas
Alpha-glucosidase inhibitors
Bile acid sequestrates
Metformin
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15
Q

What are the first generation sulfonyureas?

A 
1st gen:
Tolbutamide 
Chlorpropamide
Tolazamide
Acetohexamide
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16
Q

What are the second gen sulfonylureas?

A

Glyburide
Glipizide
Gliclazide
Glimepiride

Repaglinide
Nateglinide
Metformin
Rosiglitazone
Pioglitazone
Rosiglitazone+metformin
17
Q

What are the alpha glucosidase inhibitors?

A

Acarbose

Miglitol

18
Q

What are the incretins (GLP-1 receptor agonists)?

A

“tide”
Exenatide
Liraglutide

19
Q

What are the incretins (dipeptidyl peptidase -4 inhibitors?

A

“Gliptins”
Sitagliptin
Linagliptin
Saxagliptin

20
Q

What are the amylin analogs?

A

Primalintide

21
Q

What are the bile acid sequestrates?

A

Colesevalam hydrochloride

22
Q

What are the drug combinations almost all made with?

A 
Metformin+
    Glyburide
    Rosiglitazone
    Pioglitazone
    Glipizide
    Sitagliptin
23
Q

What are the cortisols?

A

-sones

24
Q

What is the exogenous aldosterone?

A

Fludrocortisone

25
Q

What are the antagonists of aldosterone action?

A

Spironolactone
Aminoglutethimide
Ketokonazole

26
Q

What are the exogenous PTH?

A

Teriperidide

Full length hPTH

27
Q

What are the exogenous calcitonins?

A

Synthetic human calcitonin hCT

Natural salmon calcitonin

28
Q

What are the vitamin D agents?

A 
Cholecalciferol=D3
ergosterol
ergocalciferol=D2
25-OH cholecalciferol
Calcipotriol
Dihydrotachysterol=D2
Paricalcitol
22-oxacalcitriol
calcitriol
29
Q

Cinacalcet

A

x 0958686939002

30
Q

Calcium

A

x

31
Q

Fluoride

A

x

Endocrine (15 decks)

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