Physiology: Female Sex Hormones: Dragatsis Flashcards

1
Q

How many eggs does a woman usually have?

A

400,000

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2
Q

What is the process of ovulation steps?

A
Follicle
Primordial follicle
Corpus luteum
Mature follicule (with ovum and antrium)
Ovulation

Remaining: Corpus hemorrhagium (recently ovulated)

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3
Q

What does estrogen do? Stimulate growth and hormonal secretion of ovaries and follicals to stimulate the dominant follicle

A

f

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4
Q

What are the negative and positive feedbacks of estrogen on the hypothalamus and anterior pituitary/

A

Low: inhibit LH/FSH
Rising: sitim LH/FSH–>LH surge causes ovulation
high: Inhibitory!
Very low+ progesterone: inhibitory

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5
Q

What is used in birth control pills?

A

Very low E, and Progesterone

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6
Q

Estrogen does what to oviduct?

A

+: muscle, epithelium, motility, ciliary beating

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7
Q

Estrogen does what to uterus?

A

+ Myometrium growth and contractility
+ endometrium growth, spiral artery development
+blood supply

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8
Q

Estrogen does what to the cervix?

A

Production of thin, watery, clear mucus to allow sperm to get into uterus

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9
Q

What does estrogen do to uterine circulation?

A

Antivconstrictive dilatory

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10
Q

What is estrogen effect on the vagina?

A

+lubrication
+thickness of wall
+cornification

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11
Q

What does estrogen do to the mamary glands?

A

Branching of ducts
Fat deposition, connective tissue deposition
darkeing and growth of areola and nipples

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12
Q

TEST: What type of receptors does estrogen increase in the endometrium?

A

Progesterone receptors

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13
Q

Why is it important that estrogen increases progesterone receptors in the endometrium?

A

1; Alllows endometrium to increase nutrient secretion to fertilized egg (glycogen) before implantation, in response to increased progesterone in the luteal phase
2. allows implantation invasion

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14
Q

What do estrogen and testosterone do to bones?

A

Cause closure of epiphyseal plates at end of GH

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15
Q

How does estrogen effect cholesterol metabolism?

A

Good! High HDL and low LDL, anti-atherogenic

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16
Q

What are some other effects of estrogen?

A

Increase pit size
Increase Prolactin secretion (but blocks stimulation of milk synthesis)
Anti-osteoporotic

17
Q

What does estrogen do to libido?

A

increase libido

18
Q

Progesterone does what?

A

Promote gestation (Pro-Gest)

19
Q

Effect of progesteron one uterine muscle?

A

Inhihitory: antagonizes estrogen

  • motility
  • contractions
  • oxytocin senstivity
  • excitability
20
Q

Progesterone effects on endometrium?

A

Prepares for implantation: secretions and acceptability

21
Q

Progesterone effects on pituitary?

A

Inhibit LH and FSH, especially when estrogen is present

22
Q

Progesterone effect on breasts?

A

+mammary gland growth

-milk synthesis (inhibits prolactin)

23
Q

Progesterone effect on body temp?

A

Raises body temp post ovulation

24
Q

Progesterone effect on cervix?

A

Thick, sticky secretions (prevents sperm and BACTERIA entry)

25
Q

Progesterone effect on HPit?

A

Very high: inhibitory (used in birth control)