Module 3 Summary Eukaryotic

Question 1

Exonuclease activities 3’ -> 5’

DNA Polymerase Y

DNA Polymerase 6

DNA Polymerase a

DNA Polymerase E

DNA Polymerase B

Answer 1

DNA Polymerase Y YES

DNA Polymerase 6 YES

DNA Polymerase a NO

DNA Polymerase E YES

DNA Polymerase B NO

Question 2

Exonuclease activities 5’ -> 3’

DNA Polymerase Y

DNA Polymerase 6

DNA Polymerase a

DNA Polymerase E

DNA Polymerase B

Answer 2

DNA Polymerase Y NO

DNA Polymerase 6 NO

DNA Polymerase a NO

DNA Polymerase E NO

DNA Polymerase B NO

Question 3

To DUPLICATE the DNA content of a cell during cell division

Adding NUCLEOTIDES at ___ of the GROWING DNA strand

Answer 3

DNA Polymerase

3’-OH

Question 4

Eukaryotic DNA Polymerase Types:

Responsible for replicating MITOCHONDRIAL DNA

Answer 4

DNA polymerase Y (gamma)

Question 5

Eukaryotic DNA Polymerase Types:

Main enzyme for REPLICATION in eukaryotes

Has 3’ -> 5’ Exonucleases activity for PROOFREADING

Answer 5

DNA polymerase 6 (delta)

Question 6

Eukaryotic DNA Polymerase Types:

To SYNTHESIZE PRIMERS

Responsible for the INITIATION of DNA replication

Answer 6

DNA polymerase a (alpha)

Question 7

Eukaryotic DNA Polymerase Types:

involved in the REPAIR of damaged DNA

Answer 7

DNA polymerase E (epsilon)

Question 8

Eukaryotic DNA Polymerase Types:

Involved in the REPAIR of damaged DNA

Important for BASE EXCISION REPAIR ( a process that removes damaged or incorrect bases from the DNA)

Answer 8

DNA polymerase B (beta)