Module 3 Summary Replication

Question 1

REPLICATION ERROR (3)

Answer 1

Mispairing

Insertion/Deletion

Strand Slippage

Question 2

DNA DAMAGE (3)

Answer 2

Chemical Damage

Radiation Damage

Damage due to attack by water

Question 3

Repair Systems

Answer 3

Excision Repair System

Mismatch Repair

Question 4

Excision repair system (3)

Answer 4

Base-pair excision pair

Nucleotide excision pair

Short-patch & long-patch

Question 5

ADDITION of a nucleotide with an INCORRECT BASE

Answer 5

Mispairing

Question 6

When a NUCLEOTIDE is added BETWEEN Nucleotides

Answer 6

Insertion

Question 7

When there is MISSING NUCLEOTIDE in the sequence

Answer 7

Deletion

Question 8

DNA strand can SLIP during Replication & Can cause ADDITION or DELETION of a nucleotide

Answer 8

Strand slippage

Question 9

Can alter DNA structure

Answer 9

Chemical Damage

Question 10

Damage caused by radiation

Answer 10

Radiation damage

Question 11

Cause REMOVAL of an AMINE group from the base group of a nucleotide or the LOSS of the entire base group

Answer 11

Damage due to attack by water

Question 12

Important for REMOVING damaged bases

Answer 12

Base-pair excision pair

Question 13

Excision nuclease that makes a CUT on a few nucleotides upstream

Answer 13

Nucleotide excision pair

Question 14

Remove short & long patches

Answer 14

Short-patch & long-patch

Question 15

Able to identify MISMATCH ERRORS. Damage leads to a SMALL DISTORTION in the DNA backbone

Answer 15

Mismatch Repair