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Neonatology boards > 2021 Neoreviews > Flashcards

2021 Neoreviews Flashcards

1
Q

Low agar scores at 10-20 minutes of age are associated with an increased risk of…

A

Spastic quadriplegic form of cerebral palsy

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2
Q

What is the classic triad Of IPEX syndrome?

A

Enteropathy(diarrhea), dermatitis, and type 1 diabetes..
Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked

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3
Q

What type of practice is most commonly associated with burnout?

A

Private

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4
Q

What causes Pallister Killian mosaic syndrome, what are the manifestations, and how do you diagnose it?

A

Mosaic tetrasomy of the short arm of chromosome 12. Multiple anomalies of CNS, CV, GI, GU.
Genetic evaluation of skin fibroblasts

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5
Q

Direct antiviral treatment for hep c are not currently approved for those younger than age…

A

3

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6
Q

If at any time the… valve becomes insufficient, a VSD has to be repaired regardless of symptoms.

A

Aortic

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7
Q

Carbohydrate malabsorption (diarhea) can be detected by means of … stool or the presence of fecal … substances

A

Acidic… reducing

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8
Q

Which pressor is first line in septic shock?

A

Norepinephrine

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9
Q

Severe combined immunodeficiency is associated with decreased… cell receptor … circles

A

T cell receptor excision circles

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10
Q

Mainstay pharmacological treatment for diabetes insipidus in neonates?

A

Thiazides. Diuril

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11
Q

What are the characteristics of cloacal dysgenesis sequence and why is it lethal?

A

Smooth perineum, absent urogenital and anal openings that end in abdominal cavity. Lethal because of pulmonary hypoplasia and renal failure.

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12
Q

? Should be considered in a newborn with a low resting heart rate & a family hx of unexplained syncopal events.

A

Long q t syndrome

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13
Q

Jervell and Lange-Nielsen syndrome is a rare autosomal recessive form of? Associated with profound

A

Long QT syndrome: sensorineural hearing loss.

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14
Q

Hepatoblastoma treatment?

A

Initial surgical resection versus neoadjuvant chemo determined by risk stratification

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15
Q

Therapeutic hypothermia slows the kinetics of drugs that are metabolized by phase?

A

1 metabolism: sedatives, anticonvulsants, paralyzing agents, corticosteroids.

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16
Q

Sodium deficit formula?

A

Sodium deficit (Mmol) = total body water x ( desired sodium _ serum sodium)

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17
Q

What is the biochemical marker of the skeletal dysplasia, hypophosphatasia? Tx?

A

Low alkaline phosphatase. Enzyme replacement therapy

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18
Q

Which mechanism best explains the movement of gas during hfov at the terminal bronchitis and air sacs?

A

Diffusion

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19
Q

Postnatal, ovarian cysts are observed with serial US every ? Until the infant is x months old

A

6-8 weeks. 4 months. High rate of spontaneous resolution

20
Q

Aminoglycosides exhibit? Dependent bacterial killing, requiring higher drug doses to improve bacteriocidal activity.
Blactam exhibit? Dependent bacterial killing, requiring more frequent doses.

A

Concentration
Time

21
Q

What is the most common cause of nonimmune hydrops fetalis?

A

Cardiac (25%)

22
Q

Lapse occurs because of memory? Leading to a delay in care.

A

Failure

23
Q

? Deficiency can be diagnosed based on low serum? Acid concentration & elevated ? concentrations of sulfite, xanthine, and hypoxanthine

A

Molybdenum
Uric
Urine

24
Q

Because systolic blood pressure normally? During inspiration while receiving PPV, reversed pulsus paradoxicus happens in intubated tamponade patients.

A

Increases

25
Q

Alveolar capillary dysplasia with misalignment of? Veins is often associated with anomalies of?

A

Pulmonary
Intestinal, cardiac..renal

26
Q

HLH has fever. Hepatosplenomegaly pancytopenia, and elevated?

A

Ferritin

27
Q

After a varicella exposure, all ELBW infants should get?

A

Varicella zoster immune globulin

28
Q

Early repetitive pain in preterm infants affects ? development and? Outcome

A

Thalamic
Neurodevelopmental

29
Q

Most likely toxicities of zidovudine?

A

Lactic acidosis
Hepatic dysfunction

30
Q

Which overgrowth syndrome has been associated with assisted reproductive technology?

A

Beckwidth wiedemann syndrome

31
Q

Benign familial neonatal seizures have an? Inheritance pattern, with mutations in the? Gene

A

Autosomal dominant
Kcnq3

32
Q

2 big manifestations of apert syndrome

A

Craniosynostosis
Complex syndactly hands & feet’s

33
Q

2 best markers for bone mineralization

A

Serum phosphorus and alkaline phosphatase -oop would be low /high respectively

34
Q

Babies with MTHFR deficiency have high homocysteine, progressive neuro deterioration and can be treated with?

A

betaine or/and pyridoxine ‘ homer likes butter

35
Q

On top of respiratory care, what do you perform on a baby whose mother had active Tb before delivery?

A

Lumbar puncture

36
Q

Incontinentia pigmenti presents at birth with? Extra cutaneous manifestations?

A

Skin erythema , vesicles, pustules, mimicking infection
Eyes

37
Q

At birth, influx of calcium rapidly decreases through the placenta, causing an increase in ?

A

Parathyroid hormone

38
Q

In infants born 23-27 weeks delayed card clamping is associated with lower

A

Risk of intraventricular hemorrhage

39
Q

Treatment for OTC

A

Infusion of sodium phenylacetate

40
Q

What on the chest of babies with harlequin ichthyoses decreases the risk of respiratory compromise?

A

Deep fissures= better chest mobility

41
Q

There is? Correlation between the severity of mom and neonatal myasthenia gravis anathema maternal achr antibody []? Correlate with neonatal dz.

A

No
Does not
Watch all in NICU for a bit

42
Q

CRRT:
Hemofiltration uses? To remove solutes from plasma while hemodialysis uses?

A

Convection
Diffusion

43
Q

Infants with EA/TEF require emergent ? decompression

A

.gastric (avoid perferation)

44
Q

Most drugs are transported across the placenta by?

A

Simple diffusion

45
Q

Infant getting exchange now jittery, hypertonic, prolonged QTC why?

A

Hypocalcemia

Neonatology boards (18 decks)

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