neurotransmitters and neuropharmacology

Question 1

What are the two types of synapses?

Answer 1

Indirect and direct

Question 2

What happens during a direct synapse?

Answer 2

ionotropic receptors open when bound by a transmitter- like a phone call

Question 3

WHich synapse is simple/complicated?

Answer 3

Simple- direct complicated-indirect

Question 4

Does the brain usually choose the simple or complicated way?

Answer 4

complicated

Question 5

What happens during an indirect synapse?

Answer 5

Metabotropic receptors recognize the transmitter but instead activate G protein- like passing a note in class

Question 6

75% of drugs act via which receptor type?

Answer 6

Metabotropic receptors

Question 7

WHat is an agonist?

Answer 7

Initiates normal effects of the receptor- Acts like the og cell- knock off

Question 8

What is an antagonist?

Answer 8

Prevents receptor from being activated by other ligands- opposite of drug-blocks other people from parking- COMPETITIVE

Question 9

What are the four amino acids?

Answer 9

Glutamate, Aspartate, Glycine, GABA

Question 10

What are the ionotropic receptors in Glutamate?

Answer 10

AMPA, NMDA, Kainate

Question 11

What are the ionotropic glutamate receptors?

Answer 11

Fast and direct

Question 12

What does glutamate also act on to do what?

Answer 12

Acts on m GluRs to slow metabolic receptors

Question 13

What is excitotoxicity

Answer 13

neuronal injury such as a stroke or head trauma causes excess release of glutamate, which kills neurons—cell keeps firing and eventually causes cell to commit suicide

Question 14

WHat is the most common inhibitory neurotransmitter in the brain?

Answer 14

GABA