App 10 - Pharmacokinetics Flashcards

1
Q

do you know?

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2
Q

How does ionization od drugs by the body affect their transport?

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3
Q

How are pH, pKa, and drugs related?

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4
Q

What are pH partitions in drug distribution?

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5
Q

How do we conceptualize drug ionization and pH and pKa?

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6
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7
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8
Q

What are some common log values?

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9
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10
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11
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12
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13
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14
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15
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16
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17
Q

What is ion trapping? What is its role in aspirin overdose? What about methamphetamines?

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18
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19
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20
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22
Q

What are therapeutic dosing regimens and what parameters need to be considered in them?

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23
Q

What is volume of distribution (Vd)?

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24
Q

how do you calculate Volume of distribution (Vd)?

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25
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27
Q

What is drug clearance (CL)? How do you calculate it?

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28
Q

What is Bioavailability (F)? How do you calculate it?

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30
Q

What s drug half life and how do you calculate it?

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32
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33
Q

What is a rational dosing regimen?

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34
Q

What is a maintenance does and how do you calculate it?

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35
Q

What is a loading dose and how do you calculate it?

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36
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37
Q

What are some limiations of pharmacokinetics?

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38
Q

What is therapeutic drug monitoring?

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48
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