Drugs: Mitosis Inhibitors (M phase drugs) Flashcards by Madeline Wing | Brainscape

Q

drugs ending in -tine or -taxel inhibit what

A

microtubules

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Q

Vincristine
Vinblastine

A

prevent polymerization of microtubules (mitotic spindles)

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Q

side effect of Vincristine

A

neurotoxic

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Q

side effect of Vinblastine

A

myelosuppression (no neurotoxicity)- bone marrow doesn’t make enough blood cells or platelets

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Q

Paclitaxel
Docetaxel

A

prevents depolymerization of microtubules (mitotic spindles)

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Q

side effect of paclitaxel and docetaxel

A

neurotoxic

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