Anti-infective agents: Part 1 Flashcards
It has the ability to liberate oxygen in
tissues
Oxidizing Agents
germicide, very short-acting, prone to
enzyme destruction before it reaches organisms in
wounds
Hydrogen Peroxide
A stable complex of urea and hydrogen peroxide
Commercial preparation is a solution of 12.6%
carbamide peroxide in anhydrous glycerin
Carbamide Peroxide
Other name for Carbamide Peroxide
Gly-Oxide
Carbamide Peroxide Upon addition of water
Liberation of hydrogen
peroxide
antiseptic and disinfectant, effective in
the treatment of oral ulcerations or in dental
care.
Carbamide Peroxide
Chemically unstable.
keratolytic agent and keratogenic
Induces proliferation of epithelial cells,
leading to sloughing and repair
Benzoyl Peroxide
They Inactivate protein by iodination and oxidation
Halogen Containing Compounds
Triiodomethane acts as bactericidal and fungicidal
Iodoform
An Elemental iodine (I2)
Tincture and a liniment
Iodophors
OFFICIAL PREPARATIONS IN THE USP of Halogen Containing Compounds
Iodine Tincture (2% iodine in 50% alcohol with sodium iodide)
Strong Iodine Solution (5% iodine in water with potassium iodide)
Iodine Solution (2% iodine in water with sodium iodide)
Other term for Strong Iodine Solution
Lugol’s Iodine
Iodine is also known as
Iodine salt
Iodine is admixed to increase the solubility
of the iodine and to reduce its
volatility. T/F
True
MOA of Iodine
Acts to inactivate proteins by
iodination of aromatic residues
(phenylalanyl and tyrosyl) and
oxidation (sulfhydryl groups).
