Anti-Fungal Part 1

Question 1

Discovered Trichophyton schoenleinii

Answer 1

Schönlein and Gruby

Question 2

Discovered C. albicans

Answer 2

Bernhard Von Langenbec

Question 3

Topical agents for dermatophytosis

Answer 3

Fatty acids

Question 4

SAR of Fatty acids

Answer 4

higher molecular weight members have the advantage of having lower volatility

Structure similar to sebum, a natural antifungal

Question 5

Sodium and calcium propionates

Uses: preservative, for dermatomycosis

Answer 5

Propionic acid

Question 6

Found in coconut and palm oil

Prepared from caprylic acid

Answer 6

Sodium Caprylate

Question 7

Used as topical fungicide

Astringency of zinc decreases inflammation and wetness

Answer 7

Zinc Caprylate

Question 8

Fungicide on adhesive tape

Answer 8

Zinc Propionate

Question 9

Iupac of Undecylenic acid

Answer 9

10-Undecenoic acid

Question 10

The primary fungicide for diaper rash

Answer 10

Sodium undecylenate

Question 11

Destructive distillation of castor oil (Decenex ®, Cruex ®)

Answer 11

Undecylenic acid

Question 12

Fungicidal properties are due to acetic acid formation, action is self-limiting because esterase are inactivated below a pH of 4

Answer 12

Triacetin (Enzactin, Fungacetin)

Question 13

Antiseptic and keratolytic Commonly combined with benzoic acid to form an ointment

Answer 13

Salicylic acid

Question 14

This ointment contains 6% benzoic acid and 6% salicylic acid in a petrolatum base

Answer 14

Whitfield’s ointment