L2 Cell To Cell Communication Flashcards
How do cells sense changes
Through receptors
What happens when a receptor receives info
Generates an intracellular signal
What are receptors
Proteins
Activated by stimulus
Sensitive to external and internal environmental change
Give some example of sensory receptors
Baroreceptors
thermoreceptors
Photoreceptors
What type of impulse do they respond to
Give examples
Electrical impulse
Voltage gated ion channel
Chemical
Ligand gated ion channel
What is meant by endogenous ligands
Produced by the body itself
Example of endogenous ligand
Insulin acting on insulin receptors
What are exogenous ligands
Synthesised
Example of exogenous ligands
Artificial drugs
Or
Extracted from animals / plants
4 type of receptors
Ligand gated receptors
Enzyme linked receptors
G protein receptors
Intracellular protein
Ligand
Chemical that binds to receptors
Time scale of ligand gated ion channels
Milliseconds
What happens when a ligand buns to a ligand gated ion channel
Change in membrane potential
What happens when a ligand binds to a G protein receptor
Change in excitability
Time scale of G protein receptors
Seconds