Introduction To Pharmocology Flashcards
How is drug concentration expressed
Morality
Morality
Number of drug in 1L of solvent
What is pharmacology
The study of what drugs do to a living organism
How is ligand-receptor interaction measured
Affinity
Affinity
Ability of drug to bind to receptor
What graph is used to show the affinity of a ligand
Saturation curve
What is B max
Max binding capacity
What is Kd
Affinity of ligand for its receptor
2 types of ligands
Agonist
Antagonist
Agonist ligand
Leads to a response
Antagonist ligand
Leads to no response
Potency
Ligand affinity and ability to trigger a response
What do agonist and competitive antagonist do
Compete for same binding site
How is effects of drug measured at molecular level
Receptor shape change
How is effects of drug measured at cellular level
Secretion of hormone