Introduction To Pharmocology Flashcards by Toyosi Oyabambi | Brainscape

Q

How is drug concentration expressed

A

Morality

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Q

Morality

A

Number of drug in 1L of solvent

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Q

What is pharmacology

A

The study of what drugs do to a living organism

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Q

How is ligand-receptor interaction measured

A

Affinity

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Q

Affinity

A

Ability of drug to bind to receptor

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Q

What graph is used to show the affinity of a ligand

A

Saturation curve

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Q

What is B max

A

Max binding capacity

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Q

What is Kd

A

Affinity of ligand for its receptor

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Q

2 types of ligands

A

Agonist
Antagonist

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Q

Agonist ligand

A

Leads to a response

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Q

Antagonist ligand

A

Leads to no response

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Q

Potency

A

Ligand affinity and ability to trigger a response

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Q

What do agonist and competitive antagonist do

A

Compete for same binding site

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Q

How is effects of drug measured at molecular level

A

Receptor shape change

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Q

How is effects of drug measured at cellular level

A

Secretion of hormone

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Q

How is effects of drug measured at organ level

A

Gut contractions

Q

How is effects of drug measured at body level

A

Anxiety
Depression