Chapter 3 Exam Flashcards

1
Q

Primary organs

A

site where lymphocytes matures and differentiate into antigen sensitive mature B and T cell

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2
Q

Secondary organs

A

areas where lymphocytes may encounter and bind antigen

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3
Q

name primary organ

A

thymus and bone marrow

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4
Q

name secondary organ

A

speen and lymph nodes

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5
Q

where do T cell mature

A

thymus

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6
Q

where do B cell mature

A

bone marrow

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7
Q

lymph tissue

A

acts as area for antigen sampling and processing

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8
Q

skin associated lymphoid tissue

A

SALT
langerhans cells trap antigen and present to T cell

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9
Q

Mucosal associated lymphoid tissue

A

MALT
M cells trap antigens and release them to T cells, B cells and macrophages

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10
Q

physical barrier of innate system

A
  1. skin
  2. mucous membrane
  3. lysozyme
  4. mucociliary blanket of respiratory system
  5. stomach acid
  6. intestine have normal flora
  7. urogenital tract
  8. eyes
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11
Q

bacteriocins

A

produce by flora and are lethal to related species

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12
Q

Chemical barriers

A
  1. defensive chemical in blood, lymph, and other fluids
  2. bacteriocins
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13
Q

cytokines

A

soluble cell signaling proteins

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14
Q

inflammation

A

nonspecific response to tissue injury
2 type
acute and chronic

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15
Q

acute inflammation

A

immediate response of the body to injury or cell death
follow inflammatory mediator (redness, warmth, pain, swelling, and altered function)

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16
Q

chronic inflammation

A

slow process
involves lymphocytes/macrophage and formation of new connective tissue
can cause permanent tissue damage

17
Q

cell mediated immunity

A

Based on the activity of T lymphocytes

18
Q

Cytotoxic CD8 T cells

A

attack pathogen physically and chemically

19
Q

Helper T cell (CD4)

A

stimulate B and T cell response

20
Q

anitibody mediated immunity

A

based on activity of B lymphocytes

21
Q

plasma cell

A

mature B cell
produce antibodies (binds antigen)

22
Q

epitopes

A

sites on antigen that reacts with specific T cells receptor or antibodies

23
Q

Natural acquired immunity

A

exposure to foreign substance

24
Q

natural acquire passive immunity

A

transfer of antibodies from one host to another (mother to baby)

25
Q

artificially acquire active immunity

A

results from intentional exposure to foreign material (vaccination)

26
Q

artificial acquire passive immunity

A

results after performed antibodies or lymphocytes are introduced into another host (botulinum antitoxin)

27
Q

perforin

A

toxic enzyme to produce hole in cells

28
Q

Cytokines

A

stimulate helper T cell divide into TH1 and TH2

29
Q

TH1

A

activate Cytotoxic T cells and macrophage

30
Q

TH2

A

activate B cells

31
Q

IgG

A

opsonization, neutralization, complement activation

32
Q

IgM

A

agglutination and complement activation (first in immune response)

33
Q

IgD

A

B cell to start antibody production

34
Q

IgA

A

secreted across mucosal surface

35
Q

IgE

A

parasitic infection

36
Q

latent period

A

period following initial exposure to antigen