TRANSLATION Flashcards

1
Q

process by which the information stored in a messenger RNA (mRNA) molecule is used to synthesize a protein. It occurs in the ribosomes, which are complex cellular structures.

A

TRANSLATION

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2
Q

start codon

A

AUG for Methionine

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3
Q

It binds to the start codon AUG on the mRNA, carrying the amino acid, methionine.

A

INITIATOR tRNA

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4
Q

The ribosome’s enzymatic activity, specifically the ———————————————————- _________________________________center in the large subunit, catalyzes the formation of a peptide bond between the amino acids carried by the tRNAs.

A

peptidyl transferase

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5
Q

These ————————— bind to the A-site, causing the addition of a water molecule to the polypeptide chain, resulting in its release from the final tRNA.

A

RELEASE FACTORS

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6
Q

When in translation does GTP or guanosine triphosphate became available?

A

In the initiation process of translation

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7
Q

the process in which the sequence of codons within mRNA provides the information to synthesize the sequence of amino acids that constitute a polypeptide

A

TRANSLATION

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8
Q

Start codon of translation in prokaryotes.

A

FMet or N-formlymethionine

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9
Q

Start codon of Eukaryotes

A

AUG, which codes for Methionine

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10
Q

Site of translation in Prokaryotes

A

Cytoplasm

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11
Q

Translation in Eukaryotes occurs in

A

Cytoplasm

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12
Q

template for translation

A

mRNA

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13
Q

Three adjacent ribonucleotides in mRNA corresponding to a specific amino acid

A

CODONS

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14
Q

Some amino acids are coded by more than one codon

A

DEGENERATE

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15
Q

Codons do not overlap and have no spaces in between

A

CONTIGUOUS

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16
Q

Each codon specify only one amino acid

A

UNAMBIGUOUS

17
Q

Causes dissociate of the large and small ribosomal subunit

A

IF1 and IF3

18
Q

where does the mRNA binds in the initiation process of Translation

A

small Ribosomal subunit (Shine-Dalgarno sequence)

19
Q

It bounds to the GTP, promotes the binding of the initiator tRNA to the start codon in the P-site.

A

IF2

20
Q

What are released in the initiation of the translation after the binding of IF2 to the GTP.

A

IF1, IF3, and GTP

21
Q

TRUE OR FALSE

RF1 recognizes UAG and UAA

A

True

22
Q

RF2 recognizes UGA and UAA

A

True

23
Q

TRUE OR FALSE

RF3 only assists RF1

A

FALSE, RF3 assists RF1 and RF2

24
Q

TRUE OR FALSE

The Eukaryotes require a Shine-Dalgano Sequence in the initial binding of mRNA to the Ribosome

A

FALSE,
Eukaryotes: 7-methylguanosine cap: Prokaryotes: Shine-Dalgarno Sequence

25
Q

TRUE OR FALSE

Elongation (translation) rate in prokaryotes took 15-20 amino acids per second, while eukaryotes took only 2-6 amino acids per second

A

TRUE

26
Q

UAA, UGA, UAG are

A

STOP CODONS