The Practical Lab - QA/QC Flashcards
What is important to check on machines to ensure results produced are reliable?
- setup of the system
- maintenace of analysers and system
- interpretation of the results
- checks carrier out to ensure that the values are accetable
- accurate record keeping
What are the advatages of in-house labs?
- fast turn around time
- potential for improved monitoring
- smaller volume of sample needed
- available out of hours
- available in more remote areas
- may save costs
What factors affect results?
biological and analytical
What are the biological factors prior to sampling?
intral-individual and inter-individual
What are the inter-individual factors?
inherent differences between groups of animals due to effeects of species, breed, age and/or sex
What are haematology examples for species?
cat PCV is lower than dog PCV
What are haematology examples for breed?
akitas have a lower mean cell volume than other dogs
What haematology examples are there for age?
juvenile dogs have a lower PCV and TP than adult dogs
What haematology examples are there for the sex of a patient?
males usually have higher PCV values
What are the intra-individual factors?
often due to environmental/external factors such as diet, stress/excitement, reproductive status, drugs, method/site of blood samapling
What are the pre-analytical factors?
p- poor blood sampling technique
- haemolysed, lipaemic or icteric plsma
- wrong anticoagulation to blood ratio
- sterile vs non-sterile container
- transportation
- storage
How should samples be stored if not being tested immediately?
in the fridge
How should you package a sample for postal?
- 50ml limit
- sealed contianer
- leakproof bag
- absorbative padding
- all packaged in rigid container
What are the analytical factors?
- equipment - proper function
- technician - correct training
- analytical procedure - validated technique, reagents, colibrations
- laboratoy - temperature, humidity
When is quality control performed?
during thw analysis to ensure the validity of the result