1.4Brain Disease Flashcards

1
Q

Symptoms of Parkinson’s disease

A

Small hand writing
Shuffling gait
Stooped posture
Muscle rigidity

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2
Q

Peak age of Parkinson’s disease

A

55-60

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3
Q

What part of the brain does Parkinson’s disease affect

A

The basal Ganglia

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4
Q

What is the basal ganglia

A

Group of sub cortical nuclei

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5
Q

What is the role of the basal ganglia

A

Provides fine motor control

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6
Q

What chemical is depleted in the striatum that causes Parkinson’s disease

A

Dopamine

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7
Q

Treatment for Parkinson’s disease

A

Drugs to increase brain dopamine

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8
Q

How does L-DOPA work

A

Enters brain then converts to dopamine

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9
Q

Side effects of L-DOPA

A

Uncontrollable movement

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10
Q

What is Huntington’s disease

A

Disease causing involuntary muscle jerk

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11
Q

Peak age of Huntington’s disease

A

30 - 45

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12
Q

treatment for Huntington’s disease

A

No effect treatment

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13
Q

What is addiction

A

Excessive use of a substance for non medical reasons
Brings damage to relationships

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14
Q

when animals receive rewards. What chemical is released

A

Dopamine

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15
Q

Positive symptoms of schizophrenia

A

Hallucinations
Delusions

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16
Q

Negative symptoms

A

Behaviour withdrawals

17
Q

Cognitive symptoms of schizophrenia

A

Disturbance of attention + cognition

18
Q

How does chlorpromazine work in treating schizophrenia

A

Chlorpromazine is an antagonist st dopamine receptors
- blocks dopamine in the brain

19
Q

The dopamine hypothesis

A

Schizophrenia is linked to increased dopamine

20
Q

How do atypical drugs differ to typical drugs

A

Newer
Less side effects
Both dopamine and serotonin receptors