Semaglutide Flashcards
1
Q
What class of drug is semaglutide?
A
Glucagon-like peptide 1 receptor agonist
2
Q
What are the uses of semaglutide?
A
Type 2 Diabetes mellitus in obese people
3
Q
What is the mechanism of action of semaglutide?
A
GLP-1 agonist
- increases glucose dependent synthesis of insulin secretion from B cells
- suppresses glucagon secretion
- suppresses appetite
- delayed gastric emptying
- given s.c. to prevent degradation in stomach
4
Q
What are the adverse drug reactions of semaglutide?
A
- GI upset > N+V
- pancreatitis
- decreased appetite with weight loss
- hypoglycaemia with other hypoglycaemic agents
5
Q
What are important drug drug interactions with semaglutide?
A
Other hypoglycaemic agents
