ORPTH ADONS BNGN n MLGNTN NONODNTGNC TUM Flashcards
- Irritation fibroma will be the most favored provisional diagnosis
for a firm, smooth surfaced, pinkish nodule, occurring on
(a) Buccal mucosa along the bite line
(b) Vermilion border of lip
(c) Soft palate
(d) Ala of nose
(a) Irritation fibroma being a noninflammatory, fibrous
lesion, manifests as a firm, smooth surfaced, swelling. It
represents a reactive hyperplasia of tissues in response to
local irritation/trauma. The most common cause of irritation
intraorally is occlusal trauma.
- The developmental lesion, histologically similar to giant cell
fibroma, occurring on lingual gingiva of mandibular canines is
called
(a) Procuspid papilla (b) Retromandibular papilla
(c) Retrocuspid papilla (d) Retrocuspid fibroma
(c) Retrocuspid papilla is a developmental lesion, microscopically
similar to giant cell fibroma. It occurs in children
and young adults and occurs almost exclusively on lingual
aspect of mandibular canines
- Single/multiple folds of hyperplastic tissue in alveolar vestibule,
occurring in association with flange of an ill fitting denture is
most likely to be
(a) Inflammatory papillary hyperplasia
(b) Inflammatory fibrous hyperplasia
(c) Giant cell epulis
(d) Congenital epulis
(b) This lesion is a reactive lesion occurring in response to
irritation caused by the flanges of an ill-fitting complete/
partial denture. It typically manifests as single/multiple
folds of hyperplastic tissue in alveolar vestibule.
- Fibroepithelial polyp is a flattened leaf-like pink lesion occurring
on
(a) Soft palate (b) Hard palate
(c) Gingiva (d) Labial mucosa
(b) Also called leaf-like denture fibroma, it occurs on the
hard palate beneath a maxillary denture. It manifests as a
flattened pink mass that is attached to the palate by a thin
stalk (peduncle).
- All except ____ are common causes of inflammatory papillary
hyperplasia.
(a) Ill-fitting dentures
(b) Poor denture hygiene
(c) Wearing dentures for 24 hours
(d) Infection by herpes virus
(d) Also known as denture papillomatosis, this lesion also,
like inflammatory fibrous hyperplasia occurs in response
to factors like poor oral hygiene, ill-fitting dentures, etc. It
occurs most commonly beneath a denture base on the hard
palate.
- Microscopically, one of the most common types of arrangements
of tumor cells in fibrous histiocytoma is _____ pattern.
(a) Storiform (b) Herringbone
(c) Ductal (d) Glandular
(a) Fibrous histiocytoma is a true neoplasm and exhibits both
fibroblastic and histiocytic differentiation. Characterized
microscopically by proliferation of spindle-shaped cells with
vesicular nuclei in short, interlacing fascicles, resembling
the whorled appearance of a straw mat (storiform).
- The most common cause of pyogenic granuloma is
(a) Infection by pyogenic organisms
(b) Granulomatous infection
(c) Exaggerated tissue reaction to local irritation/trauma
(d) Infection by herpes virus
(c) Initially believed to be a pyogenic infection, it is now thought
to represent an exuberant tissue reaction to local irritation/
trauma
- 75% of pyogenic granulomas occur on the
(a) Palate
(b) Tongue
(c) Gingiva
(d) Lip
(c) Gingival irritation and inflammation being the most
common causes, pyogenic granuloma occurs most
commonly on the gingivae. Other common intraoral sites
are lips, tongue and buccal mucosa
- Which amongst the following lesions does not occur commonly
on the gingiva?
(a) Peripheral ossifying fibroma
(b) Pyogenic granuloma
(c) Peripheral giant cell granuloma
(d) Neurofibroma
(d) Pyogenic granuloma, peripheral ossifying fibroma and
peripheral giant cell granuloma are included under the
differential diagnosis of epulides (swelling occurring on
gingivae). Neurofibroma, however, occurs most commonly
on tongue and buccal mucosa
- A gingival lesion which histologically shows trabeculae of osteoid
or droplets of basophilic cementum like material in a background
of fibrovascular connective tissue is suggestive of
(a) Central ossifying fibroma
(b) Juvenile ossifying fibroma
(c) Periapical cemental dysplasia
(d) Peripheral ossifying fibroma
(d) Although all other lesions show somewhat similar features
of presence of osteoid and/or cementum like material, all
of them occur centrally within the bone, while peripheral
ossifying fibroma, as the name suggests, occurs peripherally,
i.e. within soft tissue.
- Intraoral lipomas occur most commonly on
(a) Gingiva
(b) Buccal mucosa
(c) Tongue
(d) Palate
(b) Lipomas occur most commonly in areas where there are
plenty of adipocytes, which will be more in buccal mucosa
compared to palate, gingiva or tongue
- The most common histological variant of lipoma is
(a) Fibrolipoma
(b) Angiolipoma
(c) Myxoid lipoma
(d) Spindle cell lipoma
(a) This variant shows excessive fibrosis between the adipocytes
- Damage to a nerve bundle is the most common cause of
(a) Solitary circumscribed neuroma
(b) Neurilemmoma
(c) Traumatic neuroma
(d) Neurofibroma
(c) It is not a true neoplasm but an exuberant attempt at repair
of a damaged nerve trunk.
- Which amongst the following is the more common nerve tissue
tumor of head and neck region?
(a) Traumatic neuroma
(b) Schwannoma
(c) Neurofibroma
(d) Solitary circumscribed neuroma
(d) It represents a reactive lesion, with the etiology usually being
trauma. It shows a striking predilection for the face, especially
nose and cheeks.
- Microscopic pattern of Antoni A type of tissue proliferation is
found in
(a) Neurilemmoma
(b) Neurofibroma
(c) Hodgkin’s disease
(d) Verrucous carcinoma
(a) Antoni type A tissue is made up of elongated/spindle shaped
cells with spindle-shaped/wavy nuclei which are aligned in
a characteristic palisading pattern, while the intercellular
fibers are arranged in parallel fashion between the rows of
nuclei.
- _____________ is the most common location for occurrence of
neurilemmoma.
(a) Lip
(b) Tongue
(c) Palate
(d) Vestibule
(b) Although neurilemmoma shows a predilection for head and
neck region, tongue is the most common intraoral site, with
other locations being palate, floor of mouth, buccal mucosa
and gingiva
- The most common peripheral nerve neoplasm is
(a) Neurofibroma
(b) Granular cell tumor
(c) Schwannoma
(d) Solitary circumscribed neuroma
(a) This common peripheral nerve neoplasm arises from a
mixture of cell types including Schwann cells and perineural
fibroblasts
- The central, acellular, eosinophilic mass found in center of Antoni
A tissue of neurilemmoma is called
(a) Verrucous body
(b) Verruciform body
(c) Verocay body
(d) Basaloid body
(c) Verocay bodies are composed of reduplicated basement
membrane and cytoplasmic processes of the Schwann cells.
- Ancient neurilemmoma are those tumors that show _______
changes.
(a) Degenerative
(b) Myxoid
(c) Squamous metaplasia
(d) Basaloid
(a) Degenerative changes within ancient neurilemmoma
consist of hemorrhage, hemosiderin deposit, fibrosis,
inflammation and nuclear atypia.
- Neurofibroma arises from
(a) Perineural fibroblasts
(b) Schwann cells
(c) Mixture of (a) and (b)
(d) Fibroblasts
(c) Earlier believed to arise from Schwann cells, it is now
understood that it can arise from a mixture of cell types
including perineural fibroblasts
- Neurofibroma can also be a component of
(a) von Willebrand’s disease
(b) von Recklinghausen’s disease
(c) van der Waals disease
(d) von Ebner’s disease
(b) Multiple lesions of neurofibromas occurring in a person
is referred to as neurofibromatosis/von Recklinghausen’s
disease. Unlike neurofibroma though, it is a hereditary
disease, inherited as an autosomal dominant trait
- ______ cells are found in large numbers in neurofibroma, which
may be used as a diagnostic feature.
(a) Macrophages
(b) Neutrophils
(c) Lymphocytes
(d) Mast cell
(d) Neurofibroma is composed of interlacing bundles of
spindle-shaped cells with thin, wavy nuclei. These cells
are associated with delicate collagen bundles and myxoid matrix. Mast cells are numerous in the lesion and can be a
useful diagnostic featur
- Lisch nodules and Crowe’s sign are components of
(a) Neurilemmoma
(b) Neurofibroma
(c) Neurofibrosarcoma
(d) Neurofibromatosis
(d) Axillary freckling (Crowe’s sign) and translucent brownish
pigmented spots on the iris (Lisch nodules) belong to a set
of 7 features. The diagnostic criteria of neurofibromatosis
are met if a patient has 2 or more of these 7 feature
- The most common and serious complication of neurofibromatosis
is
(a) Pheochromocytoma
(b) Wilms tumor
(c) Malignant peripheral nerve sheath tumor
(d) Leukemia
(c) Neurofibrosarcoma/malignant peripheral nerve sheath
neoplasm occurs in about 5 percent of cases of neurofibromatosis.
They occur most commonly on trunk and
extremities
- Development of ________ occurs in 90% of cases of multiple
endocrine neoplasia Type 2B.
(a) Pheochromocytoma
(b) Medullary carcinoma of thyroid
(c) Wilms tumor
(d) Rhabdomyosarc
(b) This carcinoma arises from the parafollicular (C) cells
of thyroid gland which are responsible for secretion of
calcitonin. They are most often diagnosed in patients
between the ages of 18–25 and have a marked propensity
for metastasis.
- A pigmented tumor occurring in the 1st year of life, arising from
neural crest and associated with high urinary levels of vanillyl
mandelic acid is highly suggestive of
(a) MEN type 2B
(b) Melanotic neuroectodermal tumor of infancy
(c) Gingival cyst of infancy
(d) von Recklinghausen’s disease
(b) This tumor always occurs in the first year of life and is
accepted to arise from neural crest cells. Most commonly
seen in anterior maxilla as a rapidly expanding blue/black
mass. High urinary levels of VMA are seen in most neural
crest tumors like pheochromocytoma, neuroblastoma,
etc.
- Paraganglioma or carotid body tumors are derived from
(a) Ectoderm
(b) Neural plate
(c) Neural crest
(d) Mesoderm
(c) Paraganglia are specialized tissue of neural crest origin
that are associated with autonomic nerves and ganglia
throughout the body.
- The epithelioid cells in paraganglioma are arranged in nests
called as
(a) Zellballen
(b) Abtrofung
(c) Alveoli
(d) Islands
(a) These nests consist primarily of chief cells, which show
central, vesicular nuclei and a granular, eosinophilic
cytoplasm.
- The most common site of occurrence of granular cell tumor is
(a) Tongue
(b) Gingiva
(c) Palate
(d) Vestibule
(a) Uncommon benign, soft tissue tumor that shows a
predilection for oral cavity especially tongue. Earlier
believed to arise from skeletal muscles, now it is believed
to arise from Schwann cells.
- In contrast to granular cell tumor, the overlying epithelium in
congenital epulis never shows
(a) Ulceration
(b) Pseudoepitheliomatous hyperplasia
(c) Atrophy
(d) Acanthosis
(b) This tumor appears as pink red, polypoid mass on alveolar
ridge of a newborn infant and is characterized histologically
by sheets of large, closely packed, polyhedral cells showing
fine, granular eosinophilic cytoplasm.