hormones 25 Flashcards

1
Q

What are the two chemical classes of hormones?

A

Lipid soluble - hydrophobic
or water soluble - hydrophilic

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2
Q

What kind of hormones are lipid soluble?

A

Steroids eg testosterone, oestrogens, thyroid hormones and nitric oxide.

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3
Q

what kind of hormones are water soluble?

A

Amines, peptides, proteins, eicosanoids.

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4
Q

prostaglandins and leukotrienes, act locally as hormones in most tissues of body so little found in blood.

A

They are released by virtually all cells.

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5
Q

are hormones slower or faster than nerve responses?

A

Slower.

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6
Q
A
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7
Q

Describe prostaglandins.

A

Smooth muscle, blood flow, promote fever, intensify pain etc.

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8
Q

Describe leukotrienes.

A

Stimulate WBC movement and mediate inflammation.

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9
Q

What is the relationship between aspirin and ibuprofen and prostaglandin and leukotriene synthesis?

A

Aspirin & ibuprofen inhibit prostaglandin synthesis but don’t affect leukotriene synthesis.

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10
Q

What type of soluble hormone produces a second messenger called ‘Cyclic AMP’?

A

Water soluble hormone (hydrophilic)

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11
Q

How are hormones secreted?

A

In short bursts.

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12
Q

What are the secretion of hormones controlled by?

A

Negative feedback.

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13
Q

How are hormone secretions regulated?

A

Signals from nervous system,
chemical changes in blood,
other hormones.

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14
Q

Name some endocrine disorders.

A

Acromegaly - excessive GH in adults.
pituitary dwarfism - low levels of GH in children.
pituitary giantism - excessive GH levels in children.
Diabetes - insufficient insulin, type 1& 2.
Goitre - insufficient iodine, excessive thyroxine.
Hyperthyroidism - (graves disease) excessive thyroxine - goitre.
Hyperthyroidism - (myxoedema) insufficient thyroxine.

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15
Q
A
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