RNA PART III Flashcards

1
Q

Ebola virus natural host

A

fruit bat (Pteropodidae family)

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2
Q

Elbola virus can be transmitted via infected what animal?

A

Bats or primates

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3
Q

Ebola viurs is under what family?

A

Filoviridae

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4
Q

Ebola virus targets?

A

endothelial cells, phagocytes, hepatocytes

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5
Q

Ebola virus incubation period

A

2-21 days

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6
Q

can progress to DIC, diffuse hemorrhage, shock - high mortality rate (100%)

A

Ebola virus

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7
Q

Diagnosis ebola virus

A

ELISA
ANTIGEN TEST
RT PCR

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8
Q

Flaviridae viruses

A

Dengue virus
Zika virus
Yellow fever Virus
West Nile Vorus

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9
Q

Dengue virus transmission

A

bite of female Aedes aegypti mosquito (A. albopictus)

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10
Q

Dengue virus spectrum of disease

A

Dengue fever (Breakbone fever)
Dengue hemorrhagic fever

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11
Q

Dengue virus diagnosis

A

NS1 antigen, RT-PCR, Dengue IgM and IgG, and CBC (platelet count)

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12
Q

How to confirm dengue virus?

A

Perform viral culture isolation And PCR

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13
Q

Severe dengue symptoms

A

Severe plasma leakage
Severe bleeding
Severe organ impairment

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14
Q

Zika virus transmission

A

Aedes mosquito bites

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15
Q

Zika virus spectrum of disease

A

conjunctivitis, low-grade fever, muscle and joint pain, headache, and photophobia.

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16
Q

Zika virus complications

A

microcephaly and Guillain- Barre syndrome

17
Q

Yellow fever virus reservoir

A

Monkey or human

18
Q

Yellow fever virus MOT

A

bite of Aedes or Haemagogus mosquito

19
Q

Yellow fever virus spectrum of disease

A

characterized by jaundice and fever

20
Q

Prostration and shock occur, accompanied by upper gastrointestinal tract hemorrhage with hematemesis (“black vomit”)

A

Yellow fever virus

21
Q

Yellow fever virus diagnosis

A

Councilman bodies (liver biopsy)

22
Q

West nile virus transmissio

A

bites of Culex mosquito

23
Q

West nile virus spectrum of disease

A

Encephalitis

24
Q

acronym for arthropod-borne virus and
highlights the fact that these viruses are transmitted by arthropods, primarily mosquitoes and ticks.

A

Arbovirus

25
Q

Most arboviruses are classified in three families, namely

A

togaviruses, flaviviruses, and bunyaviruses