PPT RNA VIRUSES LAST Flashcards

1
Q

FILOVIRIDAE

A

Ebola Virus

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2
Q

Natural host of ebola virus

A

fruit bat (Pteropodidae family)

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3
Q

targets endothelial cells, phagocytes, hepatocytes

A

Ebola virus

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4
Q
  • can progress to DIC, diffuse hemorrhage, shock
  • high mortality rate (100%)
A

Ebola Virus

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5
Q

Diagnosis of ebola virus

A

ELISA, antigen test and RT-PCR

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6
Q

Flaviviridae

A

Dengue virus
Zika Virus
Yellow Fever Virus
West nile Virus

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7
Q

Dengue virus transmission

A

bite of female Aedes aegypti mosquito (A. albopictus)

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8
Q

Spectrum disease of dengue virus

A

Dengue fever (Breakbone fever) and Dengue hemorrhagic fever

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9
Q

Diagnosis of disease dengue virus

A

NS1 antigen, RT-PCR, Dengue IgM and IgG, and CBC (platelet count)

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10
Q

Confirmed dengue

A

Viral culture isolation
PCR

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11
Q

Zika virus transmission

A

Aedes mosquito bites, sexual and vertical transmission (possible)

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12
Q

Zika virus spectrum of disease

A

conjunctivitis, low-grade fever, muscle and joint pain, headache, and PHOTOPHOBIA .

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13
Q

Zika virus complications

A

microcephaly and Guillain- Barre syndrome

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14
Q

Yellow fever virus reservoir

A

Monkey or human

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15
Q

Mot yellow fever virus

A

bite of Aedes or Haemagogus mosquito

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16
Q

Spectrum of disease yellow fever virus

A

characterized by jaundice and fever

17
Q

Prostration and shock occur, accompanied by upper gastrointestinal tract hemorrhage with hematemesis (“black vomit”)

A

Yellow fever virus (flaviviridae)

18
Q

Diagnosis of yellow fever virus

A

Councilman bodies (liver biopsy)

19
Q

Transmission of West Nile Virus

A

bites of Culex mosquito

20
Q

Spectrum of disease west nile virus

A

Encephalitis