PPT DNA Flashcards

1
Q

Parvoviridae

A

Parvovirus B19

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2
Q

Dna Viruses

A

HHAPPPPY
Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma

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3
Q

All dna viruses have double stranded dna except

A

Parvovirus

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4
Q

All dna viruses have linear dna except

A

Papillomavirus
Polyomavirus
Hepadnavirus

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5
Q

All dna virus are icosahedral except

A

Poxvirus

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6
Q

All dna virus replicate in nucleus

A

Poxvirus

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7
Q

Parvoviridae virus

A

Parvovirus B19

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8
Q

only known human parvovirus (one serotype)

A

Parvovirus B19

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9
Q

Also known as fifth disease

A

Erythema infectiosum

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10
Q

[“slapped cheek” rash], transient
aplastic crisis, fetal infection (fetal death and “hydrops fetalis”), arthritis, : red cell aplasia,

A

Parvovirus

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11
Q

Diagnosis for parvovirus

A

Serology, PCR, Histology

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12
Q

Treatment for parvovirus

A

Supportive [I.V. immunoglobulin can be used with aplastic crisis]

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13
Q

Adenoviridae virus

A

Human adenovirus

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14
Q

Site of latency of adenoviridae

A

Replication in oropharynx

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15
Q

URT

A

Pharyngitis, conjunctivitis, coryza (serotype 3, 7, 8, 19, 37)

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16
Q

LRT

A

bronchitis, atypical pneumonia (serotype 14):

17
Q

GIT

A

acute gastroenteritis (infantile diarrhea) [serotype: 40, 41]

18
Q

GUT

A

acute hemorrhagic cystitis (serotype: 7, 11,21)

19
Q

Diagnosis for Adenoviridae

A

Cell culture (HEp-2) [Cowdry type B intranuclear basophilic inclusion bodies], EIA for gastroenteritis (40-41), PCR

20
Q

Prevention for Adenoviridae

A

Vaccine (adenovirus 4 and 7) for military recruits

21
Q

are small nonenveloped icosahedral viruses which replicate in the nucleus and may transform infected cells.

A

Papovaviruses

22
Q

HPV types 1 to 100+ (as determined by genotype; types defined by DNA homology, tissue tropism, and association with oncogenesis)

A

Papillomavirus

23
Q

SV40, JC virus, BK virus, KI, WU, Merkel cell polyomavirus (MCPyV)

A

Polyomavirus

24
Q

Double-stranded circular DNA genome replicated and assembled in nucleus

A

Papovaviridae

25
Q

Small icosahedral capsid virion

A

Papovaviridae

26
Q

Papillomaviruses

A

Human Papilloma Virus

27
Q

Human Papilloma virus transmission

A

Direct contact, sexual contact for genital warts

28
Q

Human Papilloma virus site of latency

A

Epithelial tissue (Infect squamous cells and induce formation of cytoplasmic vacuole (koilocytes)

29
Q

small, round, deeply basophilic nuclei surrounded by a clear halo and pale-staining cytoplasm

A

Koilocytes

30
Q

Papillomaviruses disease

A

Skin and Genital warts, benign head and neck tumors, anogenital
:warts

31
Q

Diagnosis Papillomaviruses

A

Cytology, DNA probes, HPV antigen