2.2 Animal Tissues, Organs and Systems Flashcards

1
Q

what is the main function of the digestive system?

A

to digest food and absorb the nutrients obtained from digestion.

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2
Q

what is the role of the pancreas and the salivary gland in the digestive system?

A

the pancreas and the salivary gland are glands which produce digestive juices containing enzymes.

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3
Q

what is the role of the stomach in the digestive system?

A

produces hydrochloric acid - which kills any bacteria present and provides the optimum acidic pH for the protease enzyme to function.

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4
Q

what is the role of the small intestine in the digestive system?

A

the small intestine is the site where soluble food molecules are absorbed into the bloodstream.

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5
Q

what is the role of the liver in the digestive system?

A

produces bile (stored in the gallbladder) which emulsifies lipids and allows the lipase enzyme to work more efficiently.

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6
Q

what is the role of the large intestine in the digestive system?

A

absorbs water from undigested food, producing faeces.

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6
Q

what is the role of enzymes in the digestive system?

A

enzymes act as biological catalysts which sped up the rate of biological reactions (the breakdown of food) without being used up.

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7
Q

how does the shape of an enzyme affect its function?

A

enzymes have a specific active site which is complementary to their substrate.

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7
Q

what is metabolism?

A

the sum of all the reactions in a cell or an organism.

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8
Q

what type of metabolic reactions do enzymes catalyse?

A
  • building larger molecules from smaller molecules e.g. glucose to starch.
  • changing one molecule to another e.g. glucose to fructose.
  • breaking down larger molecules into smaller molecules e.g. carbohydrates to glucose.
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9
Q

what is the lock and key hypothesis of enzyme function?

A

the shape of the enzyme active site and the substrate are complementary, so can bind together to form an enzyme-substrate complex.

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10
Q

how does temperature affect enzyme action?

A

up to a certain point, increasing temperature increases enzyme action, as molecules have a higher kinetic energy. above a certain temperature, the shape of the active site is altered and the enzyme becomes denatured, so it can no longer catalyse the reaction. the optimum temperature is around 37°.

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11
Q

how does pH affect enzyme function?

A

the optimum pH for most enzymes is 7 (apart from proteases in the stomach). if the pH is too extreme, the shape of the active site may be altered and the enzyme may no longer work.

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12
Q

where are carbohydrases, proteases and lipases produced in the body?

A
  • carbohydrases: amylase - salivary gland and pancreas; maltase - small intestine.
  • proteases: pepsin - stomach; others - pancreas and small intestine.
  • lipases: pancreas and small intestine.
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13
Q

what is the role of carbohydrases in the digestive system?

A

carboydrases break down carbohydrates into monosaccharides and disaccharides. amylase breaks down starch into maltose, and maltase breaks down maltose into glucose.

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14
Q

what is the role of proteases in the digesive system?

A

proteases break down proteins into amino acids.

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15
Q

what is the role of lipases in the digestive system?

A

lipases break down lipids into fatty acids and glycerol.

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16
Q

how are the products of digestion used?

A

they are used to build bigger molecules such as carbohydrates and proteins. glucose is used as substrate in respiration.

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17
Q

where is bile made and stored in the body?

A

bile is made by the liver and stored in the gallbladder

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18
Q

what is the role of bile in the digestive system?

A
  • bile is an alkaline substance which neutralises the hydrochloric acid secreted by the stomach.
  • bile emulsifies lipids to form droplets - this increases the surface area for the lipases enzyme to work on.
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19
Q

what is the heart?

A

an organ that pumps blood around the body

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20
Q

what is the purpose of the circulatory system?

A

carries oxygen and other useful substanced to bodily tissues, and removes waste substances.

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21
Q

how does the double circulatory system work?

A
  • one pathway carries blood from the heart to the lungs - where the gaseous exchange of oxygen and carbon dioxide takes place.
  • one pathway carries blood from the heart to the tissues.
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22
Q

where does blood pumped by the right ventricle go?

A

the lungs

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23
Q

where does blood pumped by the left ventricle go?

A

body tissues

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24
Q

why is the double circulatory system important?

A

it makes the circulatory system more efficient - for example, oxygenated blood can be pumped around the body at a higher pressure by the left ventricle.

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25
Q

how many chambers does the heart have and what are they called?

A

4 - right atium, right ventricle, left atrium, left ventricle.

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26
Q

why is the wall of the left ventricle thicker?

A

the left ventricle has to pump blood at a higher pressure around the whole body.

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27
Q

what are the four main blood vessels associated with the heart?

A
  • aorta (left) - carries oxygenated blood from the heart to the body.
  • pulmonary vein (left) - carries oxygenated blood from the lungs to the heart.
  • vena cava (right) - carries deoxygenated blood from the body to the heart.
  • pulmonary artery (right) - carries deoxygenated blood from the heart to the lungs.
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28
Q

what is the purpose of valves in the heart?

A

prevents the backflow of blood

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29
Q

what is the purpose of coronary arteries?

A

coronary arteries supply the heart muscle with oxygenated blood.

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30
Q

describe the process of blood flow through the heart

A
  • blood enters the right atrium via the vena cava, and the left atrium via the pulmonary vein.
  • the atria contract, forcing blood into the ventricles and causing valves to shut.
  • after the ventricles contract, blood in the right ventricle enters the pulmonary artery (to the lungs) and blood in the left ventricle enters the aorta (to the body).
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31
Q

what ios the approximate value of the natural resting heart rate?

A

70 beats per minute

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32
Q

how is the heart rate controlled?

A

heart rate is controlled by a group of cells in the right atrium which acts as a pacemaker. they release waves of electrical activity which cause the heart muscle to contract.

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33
Q

how can an abnormal heart rhythm be treated?

A

irregular heart rhythms can be treated using an artificial pacemaker, which sends out electrical signals to correct the heart’s rhythm.

34
Q

what are the three blood vessels in the body?

A
  • arteries
  • veins
  • capillaries
35
Q

how are arteries adapted for their function?

A
  • function: carry blood away from the heart.
  • thick muscle layer - adds strength to resist high pressure.
  • thick elastic layer - allows arteries to stretch and recoil - in order to withstand high pressure.
36
Q

how are veins adapted for their function?

A
  • function: carry blood towards the heart
  • wide lumen - enables low pressure
  • valves - prevent backflow of blood
37
Q

how are capillaries adapted for their function?

A
  • function: enable transfer of substances between the blood and tissues.
  • walls are one cell thick - short diffusion path.
  • permeable walls - substances can diffuse across.
  • narrow lumen - blood moves slowly - more tie for diffusion.
38
Q

how would you calculate the rate of blood flow?

A

volume of blood/number of minutes

39
Q

where are the lungs found in the body?

A

the lungs are located in the thorax (within the chest). they are protected by the ribcage and separated from the rest of the abdomen by the diaphragm.

40
Q

what tissues make up the has exchange system?

A
  • trachea
  • intercostal muscles
  • bronchi
  • bronchioles
  • alveoli
  • diaphragm
41
Q

explain how the lungs are ventilated by the action of intercostal muscles

A
  • intercostal muscles contract
  • ribcage moves upwards and outwards
  • diaphragm flatterns and volume of the chest increases
  • increased volume results in decreased pressure
  • air is drawn into lungs down pressure gradient
    the inverse occurs when air moves out of the lungs.
42
Q

describe how gad exchange occurs at the alveoli

A
  • oxygen diffuses from the alveoli into the capillary bloodstream down its concentration gradient.
  • carbon dioxide diffuses from the capillary into the alveoli down its concentration gradient.
43
Q

describe how alveoli are adapted for gas exchange

A
  • small and arranged in clusters - larger surface area.
  • rich blood supply - maintains concentration gradient.
  • thin alveolar wall - short diffusion pathway
44
Q

how would you calculate the breathing rate

A

number of breaths/number of minutes

45
Q

what substance carries the different components of blood around the body?

A

plasma

46
Q

what substances are transported by plasma?

A
  • red blood cells
  • white blood cells
  • platelets
  • carbon dioxide
  • urea
  • products of digestion
47
Q

what is plasma?

A

a yellow liquid within blood that transports substances around the body.

48
Q

what is the purpose of red blood cells in blood?

A

transport of oxygen around the body

49
Q

how are red blood cells adapted for their function?

A
  • biconcave shape - increased surcface area to volume ratio.
  • no nucleus - more room for haemoglobi to bind to oxygen.
  • contain haemoglobin - binds to oxygen.
50
Q

what is the purpose of white blood cells in blood?

A

they form part of the immune system, which protects the body from invading pathogens.

51
Q

how are white blood cells adapted for their function?

A
  • have a nucleus - contains DNA which codes for proteins
  • can produce antibodies
  • can produce antitoxins
  • can engulf and digest pathogens (phagocytosis)
52
Q

what is the purpose of platelets in blood?

A

plateles are small cell fragments which aid the clotting of blood at the site of a wound.

53
Q

why is the function of platelets important?

A

platelets aid in the process of blood clotting (conversion of fibrinogen to fibrin). as a result, red blood cells are trapped in the fibrin network, forming a clot which prevents excessive bleeding. scab formation (after the clot has dried) prevents bacteria from entering the wound.

54
Q

what is coronary heart disease?

A

coronary heart disease occurs when the coronary arteries that supply the heart muscle become blocked with a buildup of fatty material. this restricts the supply of oxygen to the heart, possibly leading to a heart attack or death.

55
Q

what is a stent and how does it work?

A

a stnet is a metal mesh tube that is inserted into a blocked artery so that it remains open. the stent is inflated using a balloon, which is later removed to allow blood to flow freely.

56
Q

what are the advantages and disadvantages of stents?

A

advantages
- insertion can be carried out without general anaesthetic
- quick recovery time
- lower the risk of a heart attack
disadvantages
- risk of postoperative infection
- risk of blood clots at site of stent

57
Q

what are statins?

A

statings are drugs which reduce the level of LDL (bad) cholesterol which contributes to the development of coronary heart disease.

58
Q

what are the advantages and disadvantages of statins?

A

advantages
- reduce risk of strokes, coronary heart disease and heart attacks
- increase levels of HDL (good) cholesterol
disadvantages
- have to be taken continuously
- may have side effects
- effect may not be immediate

59
Q

what is a heart bypass surgery?

A

a surgery where blocked coronary arteries are replaced with sections of veins taken from other parts of the body.

60
Q

what are the consequences of leaky heart valvues?

A

blood flows in the wrong direction, causing the heart to become less efficient. patients may become breathless and die as a result.

61
Q

what types of valves can replace leaky valves?

A
  • mechanical - made of metal or polymers
  • biological - taken from animals (pigs, sometimes humans)
62
Q

what are the advantages and disadvantages of mechanical valves?

A

advantages
- last for a very long time
disadvantages]
- need to take medication to prevent blood clotting around valve

63
Q

what are the advantages and disadvantages of biological valves?

A

advantages
- work very well - no medication required
disadvantages
- only lasts 12-15 years

64
Q

what is the purpose of an artificial heart?

A

artificial hearts are intended to support a patient’s heart while they wait for a suitable donor heart.

65
Q

what are the advantages and disadvantages of artificial hearts?

A

advantages
- less likely to be rejected by immune system
- allows damaged heart to rest to help recovery
disadvantages
- risk of infection due to surgery
- risk of blood clots
- have to take blood-thinning drugs

66
Q

what is health?

A

health is the state of physical and mental wellbeing

67
Q

what is a communicable disease?

A

a disease caused by a pathogen which can be transmitted from one person to another e.g. the flu.

68
Q

what is a non-communicable disease?

A

a disease which can not be transmitted from person to person e.g. cancer.

69
Q

how can diet affect health?

A
  • too little food/lack of nutrition - anaemia, vitamin deficiencies.
  • too much food/too much unhealthy food - obesity, type 2 diabetes.
70
Q

how can stress affect health?

A

prolonged stress is linked to a wide range of health problems including heart diseases, cancers and mental health issues.

71
Q

how can life situations affect health?

A

many life factors such as location, gender, financial satus, ethnic group and healthcare provision can impact a person’s mental and physical health.

72
Q

give examples of how health problems can interact

A
  • infection with certain viruses can lead to cancer e.g. hepatitis infections can lead to liver cancer.
  • a compromised immune system (e.g. due to cancer) can lead to a higher risk of infection with communicable diseases.
  • immune reactions caused by a pathogen can trigger allergic reactions.
  • problems with physical health can lead to mental health issues.
73
Q

what is a risk factor?

A

a risk factor is an aspect of a person’s lifestyle or a substance found in the body of the environment which can increase the risk of a disease.

74
Q

what is a causal mechanism?

A

a mechanuism which demonstrates how one factor biologically influences another.

75
Q

how do diet, smoking and exercise affect the development of cardiovascular disease?

A
  • diet: high levels of LDL cholesterold causes arteries to become blocked, increasing blood pressure and the risk of a heart attack.
  • smoking: nicotine increases heart rate; other chemicals damage the artery lining and increase blood pressure.
  • exercise: lowers blood pressure, readucing strain on the heart.
76
Q

how does obesity affect the developemt of type 2 diabetes?

A

obesity is strongly linked with the onset of type 2 diabetes - a disease in which the body stops responding to insulin.

77
Q

how does alcohol affect liver and brain function?

A
  • excessive long-term alcohol use may lead to liver cirrhosis (scarring of the liver)/
  • increases risk of liver cancer.
  • damages brain tissue and nerve cells.
78
Q

how does smoking affect the development of lung disease and lung cancer?

A
  • tar in tobacco can damage the alveoli of the lungs, leading to chronic obstructive pulmonary disease (COPD).
  • tar also damages the cells which line the lungs, leading to lung cancer.
79
Q

how do smoking and alcohol affect unborn babies?

A
  • carbon monoxide from tobacco smoke reduces the amount of oxygen to foetus receives, which can lead to premature birth or stillbirth.
  • alcohol passes across the placenta and damages the developing foetus. once born, the baby may hae a number of deformities and health problems as part of foetal alcohol syndrome.
80
Q

how do carcinogens affect the development of cancer?

A

ionising radiation is a type of carcinogen which can cause mutations in DNA, potentially leading to cancer.

81
Q

what is cancer?

A

cancer is the development of a tumour as a result of uncontrolled cell division.

82
Q

what is a benign tumour?

A
  • a tumour that is contained in one location, usually within a membrane.
  • they are not cancerous and do nmot invade other parts of the body.
  • can grow large very quickly - may cause damage to another organ.
83
Q

what is a malignant tumour?

A
  • a tumour that can spread around the body via the blood and lymphatic system.
  • can invade other tissues (metastasis).
  • cells divide more rapidy and have a longer lifespan.
  • disrupts healthy tissues and may lead to death.
84
Q

give examples of factors which can lead to cancer

A
  • genetics - certain genes increase the risk of brease and overtian cancer
  • smoking
  • obesity
  • ionising radiation -UV light and X-rays
  • viral unfections -HPV and cervical cancer