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CLINICAL CHEMISTRY (LEC) > Proteins part 2 > Flashcards

Proteins part 2 Flashcards

1
Q

Contain peptide chains which on hydrolysis yield only amino acids

A

Simple proteins

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2
Q

May be fibrous or globular in shape

A

Simple proteins

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3
Q

Simple proteins shape can be?

A

Fibrous or globular

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4
Q

What is the composition of conjugated proteins?

A

Apoprotein and prosthetic group/ protein and non-protein moiety

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5
Q

Proteins generates energy through?

A

Catalysts and electron transfer.

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6
Q

Through contractile elements, proteins produce ___________.

A

Motility

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7
Q

Serves as ____________ hormones and cytokines for intercellular regulation

A

receptor

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8
Q

Increase protein synthesis

A

GH, Insulin and Thyroid hormone

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9
Q

Increase protein catabolism

A

Glucocorticoids and Glucagon

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10
Q

___________ denatures the protein making them susceptible to enzyme digestion.

A

High acidity

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11
Q

This digest proteins into amino acids

A

Pepsin

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12
Q

What are the major plasma proteins?

A

Albumin, Globulins and Fibrinogen

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13
Q

What does the liver produces?

A

albumin, a-1, a-2, B-globulins and fibrinogen

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14
Q

What do the RES produces?

A

Gamma globulin

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15
Q

migrates anodal than the Albumin

A

Pre-albumin

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16
Q

Second most predominant protein in CSF

A

Pre-albumin

17
Q

Functions as a carrier protein for thyroid hormones and Vitamin A.

A

Pre-albumin

18
Q

Pre-albumin functions as a carrier protein for?

A

Thyroid hormones and Vitamin A.

19
Q

Albumin is derived from the latin word?

A

Albus

20
Q

What is the meaning of Albu

A

White

21
Q

What is the lifespan of Albumin?

A

15-19days

22
Q

Largest protein fraction

A

Albumin

23
Q

If the Albumin is the largest fraction, it is equivalent to how many percent?

A

52-62%

24
Q

Pressure exerted by the proteins in the blood plasma that tends to pull water to the circulation. Therefore, preventing extravasation into the tissues

A

osmotic pressure

25
Q

It decreases during inflammation.

A

Negative acute phase reactant

26
Q

High serum albumin levels are associated with ___________, _____________ or ________________.

A

dehydration
prolonged tourniquet application
specimen evaporation.

27
Q

What do the following causes?

  • inflammation,
  • hepatic disease,
  • urinary loss due to kidney problems,
  • gastrointestinal loss,
  • protein-calorie malnutrition,
  • burn injury,
  • edema
  • ascites
A

Low serum levels

28
Q

Absence of albumin

A

Analbuminemia

29
Q

Decreased level of albumin

A

Hypoalbuminemia

30
Q

In hypoalbuminemia, first and second degree refers to?

A

1 - Liver damage
2 - Diminished protein intake

31
Q

Malabsorption or malnutrition

A

Hypoalbuminemia

32
Q

Nephrotic syndrome

A

Hypoalbuminemia

CLINICAL CHEMISTRY (LEC) (23 decks)

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