Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CLINICAL CHEMISTRY (LEC) > LIVER FUNCTION TEST part 2 > Flashcards

LIVER FUNCTION TEST part 2 Flashcards

1
Q

What is the other name for Jaundice?

A

Icterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What causes the yellow discoloration of the plasma, skin, sclerae & mucous membranes?

A

Bilirubin accumulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

It may be the first and often the only manifestation of liver disease.

A

Jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Jaundice is clinically apparent when serum total Bilirubin reaches ____________.

A

2-3 mg/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the other signs of disturbances in Bilirubin metabolism?

A

Dark urine
Acholic stool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

a deposition of bilirubin in the brain

A

Kernicterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

occurs when scar tissues are replaces a healthy normal liver tissues

A

Cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the pressure for Portal Hypertension?

A

> 20mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

influx from the abdominal portion of the digestive tract, pancreas & spleen

A

Portal Vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the pressure for Portal vein?

A

-5-10 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

accumulation of fluid within the peritoneal cavity

A

Ascites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

In hepatic dysfunction __________ undergo limited or aberrant transformation, accumulate & exert unwanted effects

A

Drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

drugs undergo limited or aberrant transformation, accumulate & exert unwanted effects

A

ALTERED DRUG METABOLISM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

This increased estrogen effect, this happens among men.

A

Feminization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hormone Imbalance

A

ENDOCRINE ABNORMALITIES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

alterations in glucose metabolism due to _________________.

A

Insulin resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

the liver efficiently sequesters dimeric Ig A & secretes it into the bile.

A

IMMUNOGLOBULIN ABNORMALITIES

18
Q

defects in uptake —> increase serum IgA

A

Liver disease

19
Q

alteration in hemostasis and a generalized hemorrhagic tendency

A

DISORDERED HEMOSTASIS

20
Q

when RBC are destroyed, hemoglobin is released

A

Hepatic Excretory Function

21
Q

What transported the the hemoglobin in the plasma?

A

Haptoglobin

22
Q

in cases of severe RBC destruction, ___________in plasma increases which then causes the __________ of the available ________

A

hemoglobin
utilization
haptoglobin

23
Q

What happens to the level of Haptoglobin during the increase of RBC destruction?

A

Decreases

24
Q

when hemoglobin can no longer be transported by haptoglobin, the hemoglobin molecules are then broken down into _____________

A

“heme” and “globin”

25
Q

is the protein portion of the hemoglobin and will be recycled by the liver

A

Globin

26
Q

is transported by the protein carrier known as hemopexin

A

Heme

27
Q

when hemopexin is depleted, heme is divided into ________________.

A

iron and protoporphyrin

27
Q

What happens to hemopexin when heme levels increase?

A

Decreases

28
Q

What transported iron into the bone marrow and to be used in the synthesis of new RBC?

A

Transferrin

29
Q

the protoporphyrin is now broken down into ___________ and further broken down into ______________ particularly the _____________form

A

biliverdin
bilirubin
unconjugated

30
Q

the unconjugated bilirubin is then transported by _________ towards the site of conjugation which is the liver

A

albumin

31
Q

in the liver cells, unconjugated bilirubin is converted into conjugated bilirubin through the action of the enzyme ______________, this process occurs in the ________ of the liver cell

A

Uridyl diphosphate glucuronyl transferase ( UDPGT)
smooth ER

32
Q

then conjugated bilirubin goes out of the liver down to the _______ and it is emptied into the ________

A

bile duct
intestine

33
Q

In the intestine, the conjugated bilirubin is
converted into the __________

A

urobilinogen

34
Q

What organ in conjugated bilirubin is converted into urobilinogen?

A

Intestine

35
Q

is a colorless substance formed in
the intestine

A

Urobilinogen

36
Q

Urobilinogen is converted into?

A

urobilin

37
Q

is an orange-brown pigment which is
responsible for the natural brown color of the
stool

A

Urobilin

38
Q

TRUE OR FALSE:
normal urine may contain urobilinogen

A

true

39
Q

Organic anions of both endogenous & exogenous origin are removed from the _______ and excreted into the ________

A

sinusoidal blood
bile

CLINICAL CHEMISTRY (LEC) (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions