Proteins part 5 Flashcards

1
Q
  • Causes y-globulins to migrate toward the cathode even though they are slightly (-) charged
  • Due to electrical charge on support medium
A

ELECTROENDOSMOSIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
  • Relative concentration of each bond determined by _____________?
A

densitometry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Plasma samples result in fibrinogen peak between gamma and beta fractions

A

Specimen collection and handling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
  • Due to IgA (in serum); Cirrhosis
  • Seen in patients with liver cirrhosis cause by increase in IgA
A

 Beta-gamma bridging effect:

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
  • Monoclonal gammopathy (Multiple myeloma)
A

 Monoclonal band (gamma-globulin);

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
  • Chronic inflammation
A

 Poluclonal band

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
  • nephrotic syndrome
A

 Increase in a-2-macroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

deficiency in a-a-antitrypsin; Juvenile cirrhosis

A

 a-1-globulin flat curve:

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
  • Seen in patients with Monoclonal gammopathy
A

Gamma spike:

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
  • Seen in patients with emphysema
A
  • A-1-antitrypsin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q
  • Increased beta region, use plasma instead of serum.
A
  • A-1-antitrypsin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the reference range for total protein and Albumin?

A
  • Total protein: 6.5 – 8.3g/dL
  • Albumin: 3.5 – 5.5g/dL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly