FUNGAL INFECTIONS

Question 1

What is tx for aspergillosis?

Answer 1

Voriconazole

Question 2

What is cryptococcosis?

Answer 2

Amphotericin B

Question 3

What is tx for vaginal thrush?

Answer 3

Clotrimazole or fluconazole

Question 4

What is tx for oral thrush?

Answer 4

Nystatin

Miconazole

fluconazole

Question 5

What is nail fungal infection tx?

Answer 5

Topical -

If not systemic - terbinafine or itraconazole

Question 6

When to refer if nail fungal infection?

Answer 6

If under 18

diabetes

pregnant/ breastfeeding

More than 2 nails infected

Question 7

2 main SEs of anti-fungals?

Answer 7

QT prolongation

hepatotoxic

Question 8

What improves itraconazole bioavailability?

Answer 8

Fizzy drinks

Question 9

What antifungal is lower risk of QT prolongation + hepatotoxicity?

Answer 9

Fluconazole

Question 10

What anti-fungal has life threatening hepatotoxicity?

Answer 10

Ketokonazole - oral tx suspended

Question 11

What reaction occurs with voriconazole use?

Answer 11

phototoxicity

Question 12

What organ failure can amphotericin B cause?

Answer 12

Renal failure

Question 13

Risk of —— in IV amphotericin B ?

Answer 13

Anaphylaxis - TEST dose within 3p0 mins

maintain same formulation