PRINCIPLES OF ANTIMICROBIAL THERAPy Flashcards by wendy Unknown | Brainscape

Q

lowest concentration of antibiotic

A. Minimum Inhibitory Concentration (MIC)
B. Minimal Bactericidal Concentration (MBC)

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

does not kill the organism

A. Minimum Inhibitory Concentration (MIC)
B. Minimal Bactericidal Concentration (MBC)

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

minimum concentration of antibiotic

A. Minimum Inhibitory Concentration (MIC)
B. Minimal Bactericidal Concentration (MBC)

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

arrest the growth & replication of bacteria at serum level achievable in the patient, limiting the spread of infection

A. BACTERIOSTATIC DRUGS
B. BACTERICIDAL DRUGS

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CHON synthesis inhibitors

A. BACTERIOSTATIC DRUGS
B. BACTERICIDAL DRUGS

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

→ kill the bacteria at drug serum level achievable in the patient
→ more aggressive

A. BACTERIOSTATIC DRUGS
B. BACTERICIDAL DRUGS

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

cell wall synthesis inhibitors

A. BACTERIOSTATIC DRUGS
B. BACTERICIDAL DRUGS

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

T/F

the hydrophobic molecule are concentrated in the cell bilayer
and cannot enter the cell

A

T

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

T/F

the hydrophilic molecules concentrate in the blood, cytosol, or
cytoplasm and easily enter the cell

A

T

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

→ antimicrobial action must be present at the wound site at the time of its closure
→ preventive treatment

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

prophylaxis may be used to protect the healthy persons from acquisition of or invasion by specific organisms to which they are
exposed

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

delivery of treatment prior to development of symptoms

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

early treatment for patients with lab tests indicating them as an asymptomatic patient

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

aborts impending disease

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

significant risk of serious morbidity

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

C

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

for patients with unknown origin of infection

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

C

Q

drug of choice is influenced by the site of infection and history
of infection of the patient

A. PROPHYLACTIC TREATMENT
B. PRE-EMPTIVE TREATMENT
C. EMPIRIC TREATMENT
D. DEFINITIVE TREATMENT WITH KNOWN PATHOGEN
E. POST-TREATMENT SUPPRESSIVE TREATMENT

A

C

Q

T/F

In POST-TREATMENT SUPPRESSIVE TREATMENT initially, the disease is controlled by antimicrobial treatment and this treatment is continued at a lower dose if the infection is not yet completely eradicated

A

T

Q

patients with bacterial meningitis or endocarditis is given through?

A

IV

Q

patients with nausea and vomiting, gastrectomy, or disease that
may impair oral absorption is given through?

A

IV

Q

persistent suppression of microbial growth after levels of antibiotics have failed below MIC

A. Post-Antibiotic Effect
B. Time-Dependent Killing
C. Concentration-Dependent Killing

A

A

Q

acting only single or limited group of organisms

A. narrow-spectrum antibiotics
B. extended-spectrum antibiotics
C. broad-spectrum antibiotics

A

A

Q

effective against Gram (+) organisms and Gram (-)
organisms

A. narrow-spectrum antibiotics
B. extended-spectrum antibiotics
C. broad-spectrum antibiotics

A

B

Q

greater coverage for plenty of microbial species

A. narrow-spectrum antibiotics
B. extended-spectrum antibiotics
C. broad-spectrum antibiotics

A

C

Q

maximal level of antibiotic that can be tolerated by the host does not halt the growth of the pathogen

A

DRUG RESISTANCE

Q

indicated for individuals who are at high risk for temporary exposure to selected virulent pathogens & in patients who are at high risk for developing infection because of underlying disease (ex.: endocarditis)

A

NON-SURGICAL PROPHYLAXIS