2/26/15 Flashcards
(15 cards)
what is pulsus paradoxus
decrease in systolic blood pressure greater than 10mmHg with inspiration, here korotkoff sounds first
(due to cardiac tamponade, percarditis, obstructive lung disease, restrictive cardiomyopathy)
-heard first during expiration then audible during all
-can’t hear during inspiration because increased blood return pushes ventircular septum left and reduces diastolic volume and stroke volume
do beta adrenergic agonist increase/decrease cAMP
increases
why use a d-xylose test
mono sacc so don’t need pancreatic enzyjmes
-can dinstinguish GI from pancreatic malabsorption
what part of brain is atrophied mainly in alzheimer?
HIOPPOCAMPUS
b12 deficiency can cause what kind of neurological symtpoms
- combined degeneration
- dorsal + corticospinal tract
- loss of position, vibration sesnation, ataxia, and spastic paresis
factors that are chemotactic
c5a, leuktotriene B4, and 5-HETE
what is fibromyalgia
- women 20-50
- diffuse musculoskeletal pain, insomnia, and emotional disturbances
what is henoch schonlein purpura (HSP)
- most common small vessel vasculitis in children
- in young children (boys) after viral/strep infection of upper respiratory
-IgA mediated, cause abdominal pain, joint pain, lower extremity palpable purpura, and hematuria
which vasculitis is associated with transmural inflammation and fibrinoid necrosis
PAN (poly arteritis nodosa)
what drug can provoke coronary vasospasm?
ergonovine: ergot alkaloid that can stimulate alpha adrenergic and serotonergic receptors. Induces coronary spasm
wide fixed splitting of S2 heart sound indicates what?
ASD
symptoms of medulloblastoma? location?
- in cerebellum
- appear as SHEETS fo small blue cells
idiopathic membranous neoprhopathy is associated with what Ab and recetpro?
IgG4 to phospholipase A2 recetpor
what is arnold chiari?
congenital malformation
- impaired development of posterior fossa
- things like cerebellum and medulla herniate through foramen magnum
type I vs type II arnold chiari
type I: not as bad, manifests in adults as headaches and cerebellar symtpoms like ataxia
type II: more severe, can present in enonate. Abnormaly formed cerebellum and meddula. Cna get lumbar myeloningocele (leg paralyssis) or hydrocephalus (aqueductal stenosis)
